assay
98%
mp
147-150 °C (lit.)
SMILES string
NNC(=O)c1ccccc1O
InChI
1S/C7H8N2O2/c8-9-7(11)5-3-1-2-4-6(5)10/h1-4,10H,8H2,(H,9,11)
InChI key
XSXYESVZDBAKKT-UHFFFAOYSA-N
法规信息
新产品
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Xuefei Cao et al.
Current cancer drug targets, 9(2), 189-201 (2009-03-12)
Previously, we described a series of salicylhydrazide compounds with potent anti-cancer activities against a panel of human cancer cell lines derived from different origins. Preclinical evaluation showing efficacy both in vitro and in vivo in human cancer models indicated that
Laith Q Al-Mawsawi et al.
Bioorganic & medicinal chemistry letters, 17(23), 6472-6475 (2007-10-24)
The previously discovered salicylhydrazide class of compounds displayed potent HIV-1 integrase (IN) inhibitory activity. The development of this class of compounds as antiretroviral agents was halted due to cytotoxicity in the nanomolar to sub-micromolar range. We identified a novel class
Paul S Francis
Luminescence : the journal of biological and chemical luminescence, 19(4), 205-208 (2004-08-03)
The chemiluminescence accompanying the oxidation of salicylic hydrazide (2-hydroxybenzoic acid hydrazide) with hypochlorite, hypobromite, N-chlorosuccinimide, N-bromosuccinimide or hydrogen peroxide with cobalt(II) matched the photoluminescence emission of salicylic acid. In a related reaction, the oxidation of a mixture of isoniazid and