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Merck
CN

A2898

4-氨基联苯

≥98%

别名:

4-氨基联苯, 4-联苯胺, 4-苯基苯胺, NSC 7660, 对氨基苯胺, 联苯-4-基胺, 联苯基胺

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关于此项目

线性分子式:
C6H5C6H4NH2
化学文摘社编号:
分子量:
169.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-177-1
Beilstein/REAXYS Number:
386533
MDL number:
Assay:
≥98%
Form:
solid
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Quality Level

assay

≥98%

form

solid

autoignition temp.

842 °F

bp

191 °C/15 mmHg (lit.)

mp

52-54 °C (lit.)

SMILES string

Nc1ccc(cc1)-c2ccccc2

InChI

1S/C12H11N/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H,13H2

InChI key

DMVOXQPQNTYEKQ-UHFFFAOYSA-N

Gene Information

human ... UGT1A4(54657)

Application

  • 诱导人膀胱癌细胞和小鼠膀胱组织DNA损伤(致癌物)
  • 用于富集、消耗和一步纯化水蛭蛋白的合成胺配体

Biochem/physiol Actions

实验动物模型的肝肿瘤引发剂。


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pictograms

Health hazardExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

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商品

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.


Dexian Dong et al.
Journal of molecular recognition : JMR, 21(3), 163-168 (2008-04-29)
Although the concept of affinity purification using synthetic ligands had been utilized for many years, there are few articles related to this research area, and they focus only on the affinity purification of specific protein by a defined library of
K L Dooley et al.
Cancer letters, 62(3), 205-209 (1992-03-15)
The tumorigenic activities of four representative heterocyclic amine food pyrolysates, 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), were assessed in the neonatal male B6C3F1 mouse and were compared with that of the potent human carcinogen, 4-amino-biphenyl (4-ABP). These
Moinuddin et al.
Environmental toxicology, 29(5), 568-576 (2012-05-23)
4-Aminobiphenyl (4-ABP), an aromatic amine is a major environmental carcinogen found mainly in cigarette smoke. It has been vastly implicated in mutagenesis and cancer development. In this study, commercially available human placental DNA was exposed to 4-ABP (1.3 mM) in



全球贸易项目编号

货号GTIN
A2898-25G04061833359877
A2898-1G04061833359860
A2898-5G04061833359884