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线性分子式:
CH3OC6H4NH2
化学文摘社编号:
分子量:
123.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-963-1
Beilstein/REAXYS Number:
386210
MDL number:
Assay:
≥99%
Form:
liquid
InChI
1S/C7H9NO/c1-9-7-5-3-2-4-6(7)8/h2-5H,8H2,1H3
InChI key
VMPITZXILSNTON-UHFFFAOYSA-N
SMILES string
COc1ccccc1N
assay
≥99%
form
liquid
refractive index
n20/D 1.574 (lit.)
bp
225 °C (lit.)
mp
3-6 °C (lit.)
density
1.092 g/mL at 25 °C (lit.)
Quality Level
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General description
邻-甲氧基苯胺是一种芳香胺,用于合成染料、颜料和药物的合成砌块。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Muta. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
212.0 °F - closed cup
flash_point_c
100 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
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We investigated the ability of hepatic microsomes from rat and rabbit to metabolize 2-methoxyaniline (o-anisidine), an industrial and environmental pollutant and a bladder carcinogen for rodents. Using HPLC combined with electrospray tandem mass spectrometry, we determined that o-anisidine is oxidized
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Toxicological sciences : an official journal of the Society of Toxicology, 127(2), 348-359 (2012-03-10)
2-Methoxyaniline (o-anisidine) is an industrial and environmental pollutant causing tumors of urinary bladder in rodents. Here, we investigated the formation and persistence of DNA adducts in the Wistar rat. Using the (32)P-postlabeling method, three o-anisidine-derived DNA adducts were found in
Marie Stiborová et al.
Mutation research, 500(1-2), 49-66 (2002-03-14)
2-Methoxyaniline (o-anisidine) is a urinary bladder carcinogen in both mice and rats. Since the urinary bladder contains substantial peroxidase activity, we investigated the metabolism of this carcinogen by prostaglandin H synthase (PHS), a prominent enzyme in the urinary bladder, and
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