C003
(R)-(-)-3-奎宁环基二苯乙醇酸酯
别名:
(R)-(-)-QNB, (R)-(-)-奎宁环基-α-羟基二苯基乙酸酯
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C21H23NO3
化学文摘社编号:
分子量:
337.41
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Form:
solid
form
solid
Quality Segment
storage temp.
2-8°C
SMILES string
OC(C(=O)O[C@H]1CN2CCC1CC2)(c3ccccc3)c4ccccc4
InChI
1S/C21H23NO3/c23-20(25-19-15-22-13-11-16(19)12-14-22)21(24,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-10,16,19,24H,11-15H2/t19-/m0/s1
InChI key
HGMITUYOCPPQLE-IBGZPJMESA-N
Gene Information
rat ... Chrm1(25229), Chrm2(81645), Chrm3(24260)
Application
(R)-(-)-3-Quinuclidinyl benzilate can be used as a reactant for the synthesis of quaternary ammonium derivatives of (3R)-quinuclidinol esters as potential muscarinic M3 antagonists. It can also be employed in the preparation of potent muscarinic cholinergic antagonist (R)-[N-methyl-3H]quinuclidinyl benzilate methiodide by alkylation with methyl iodide.
- Pharmacological agent used as muscarinic M3 antagonist for the inhaled treatment of chronic obstructive pulmonary disease (COPD)
Biochem/physiol Actions
非选择性毒蕈碱型乙酰胆碱受体拮抗剂。更有效的 QNB 对映体。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges