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Merck
CN

D68401

2,4-二氯-1-硝基苯

97%

别名:

1,3-二氯-4-硝基苯, 不对称硝基间二氯苯

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关于此项目

线性分子式:
Cl2C6H3NO2
化学文摘社编号:
分子量:
192.00
EC Number:
210-248-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1451655
MDL number:
Assay:
97%
Form:
solid
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InChI key

QUIMTLZDMCNYGY-UHFFFAOYSA-N

InChI

1S/C6H3Cl2NO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H

SMILES string

[O-][N+](=O)c1ccc(Cl)cc1Cl

assay

97%

form

solid

bp

258 °C (lit.)

mp

29-32 °C (lit.)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B - Muta. 2 - Skin Sens. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Maja Aleksic et al.
Toxicology in vitro : an international journal published in association with BIBRA, 22(5), 1169-1176 (2008-04-29)
A large proportion of allergic skin reactions are considered to be the result of skin exposure to small organic chemicals that possess the intrinsic ability to covalently modify skin proteins, either directly or following activation. In the absence of information
Makoto Ohnishi et al.
The Journal of toxicological sciences, 34(2), 233-237 (2009-04-02)
Oral administration of 2,4-dichloro-1-nitrobenzene (2,4-DCNB) causes kidney tumors in the rat. The objective of the present study was to identify the chemical structure of 2,4-DCNB metabolites in urine. Urine from 2,4-DCNB fed rats was more yellow than urine from control
P A Botham et al.
The British journal of dermatology, 117(1), 1-9 (1987-07-01)
The fate of 2,4-dinitrochlorobenzene, a potent contact sensitizing chemical, and 2,4-dichloronitrobenzene, a non-sensitizer, was compared following their application to the skin of BALB/c mice. Although both chemicals were able to bind to protein in vitro and were capable of being
V Breinholt et al.
Cancer letters, 154(2), 201-210 (2000-05-12)
The administration of lycopene to female rats at doses ranging from 0.001 to 0.1 g/kg b.w. per day for 2 weeks was found to alter the drug-metabolizing capacity and antioxidant status of the exposed animals. An investigation of four cytochrome
Bruno Miguel Neves et al.
Toxicology letters, 177(1), 74-82 (2008-02-19)
The development of non-animal methods for skin sensitization testing is an urgent challenge. Some of the most promising in vitro approaches are based on the analysis of phenotypical and functional modifications induced by sensitizers in dendritic cell models. In this

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