H17082
2-肼吡啶
97%
别名:
2-吡啶基肼
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关于此项目
经验公式（希尔记法）:
C5H7N3
化学文摘社编号:
分子量:
109.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
225-566-8
Beilstein/REAXYS Number:
109984
MDL number:
产品名称
2-肼吡啶, 97%
InChI key
NWELCUKYUCBVKK-UHFFFAOYSA-N
InChI
1S/C5H7N3/c6-8-5-3-1-2-4-7-5/h1-4H,6H2,(H,7,8)
SMILES string
NNc1ccccn1
assay
97%
bp
90-92 °C/1 mmHg (lit.)
mp
41-44 °C (lit.)
storage temp.
2-8°C
Quality Level
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Application
- 增强金属去除功能：利用由2-肼吡啶衍生的希夫碱功能化双醛淀粉，在增强溶液中Cu(II)的去除方面显示出显著的潜力。该研究包括制备方法、性能评估和DFT计算，展示了其在水处理技术中的功效（Liang et al., 2024）。
- 双感测探头发展：研制了一种新型的含2-肼吡啶的双氰异佛隆探针，用于近红外荧光双传感Zn(2+)和Cd(2+)。这一进步有助于检测和分析各种环境和生物样品中的重金属（Yan et al., 2023）。
- 赖氨酸氧化酶活性位点分析：该研究深入了解了赖氨酸氧化酶样2活性位点组分的空间排列，包括2-肼吡啶的作用，这对于理解酶的机制和潜在的治疗应用至关重要（Meier et al., 2022）。
- 赖氨酸氧化酶的结构分析：研究重点是预测赖氨酸氧化酶样2的胺氧化酶结构域的三维结构，探索2-肼吡啶促进的相互作用动力学。这对分子生物学和酶功能分析领域意义重大（Meier et al., 2022）。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
E S H El Ashry et al.
Nucleosides, nucleotides & nucleic acids, 23(3), 567-580 (2004-04-29)
Reaction of 2-hydrazinopyridine (1) with D-xylose, D-galactose, D-glucose and D-fructose afforded the corresponding hydrazones mainly in the acyclic forms 2, 3, 6 and 11 with minor amounts of the cyclic structures. Oxidative cyclization of the hydrazones with bromine in methanol
Emma Jakobsson et al.
Acta crystallographica. Section D, Biological crystallography, 61(Pt 11), 1550-1562 (2005-10-22)
Semicarbazide-sensitive amine oxidase (SSAO) belongs to a ubiquitous family of copper-containing amine oxidases (CuAOs). SSAO is also known as vascular adhesion protein-1 (VAP-1) and has been identified as one of the adhesion molecules involved in the leukocyte-extravasation process. The structure
Design and synthesis of a new class of membrane-permeable triazaborolopyridinium fluorescent probes.
Sudath Hapuarachchige et al.
Journal of the American Chemical Society, 133(17), 6780-6790 (2011-04-09)
A new class of fluorescent triazaborolopyridinium compounds was synthesized from hydrazones of 2-hydrazinylpyridine (HPY) and evaluated as potential dyes for live-cell imaging applications. The HPY dyes are small, their absorption/emission properties are tunable through variation of pyridyl or hydrazone substituents
P Knowles et al.
Journal of neural transmission (Vienna, Austria : 1996), 114(6), 743-746 (2007-04-05)
Tranylcypromine (TCP), an amphetamine, is a reversible inhibitor of copper-containing amine oxidases. We have solved the structure of the complex of TCP with the amine oxidase from E. coli (ECAO) and shown that only the (+)-enantiomer of TCP binds. Kinetic
Minae Mure et al.
Biochemistry, 44(5), 1583-1594 (2005-02-03)
Adduct I (lambda(max) at approximately 430 nm) formed in the reaction of 2-hydrazinopyridine (2HP) and the TPQ cofactor of wild-type Escherichia coli copper amine oxidase (WT-ECAO) is stable at neutral pH, 25 degrees C, but slowly converts to another spectroscopically
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