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H4530

7-羟基黄酮

≥98%

别名:

7-羟基-2-苯基-4-4H-1-苯并吡喃-4-酮, NSC 94258

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关于此项目

经验公式（希尔记法）:
C15H10O3
化学文摘社编号:
6665-86-7
分子量:
238.24
NACRES:
NA.22
PubChem Substance ID:
57654239
UNSPSC Code:
12352100
EC Number:
229-705-3
MDL number:
MFCD00006835
Assay:
≥98%
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assay

≥98%

mp

245-247 °C (lit.)

SMILES string

Oc1ccc2C(=O)C=C(Oc2c1)c3ccccc3

InChI

1S/C15H10O3/c16-11-6-7-12-13(17)9-14(18-15(12)8-11)10-4-2-1-3-5-10/h1-9,16H

InChI key

MQGPSCMMNJKMHQ-UHFFFAOYSA-N

Gene Information

mouse ... Hexa(15211)
rat ... Ar(24208), Gabra2(29706)

Application

作为如下过程的反应物：
  • 在 O-糖基化反应中作为具有生物学价值的受体
  • 参与合成完全磷酸化的黄酮类化合物，用作胰腺胆固醇酯酶抑制剂
  • 用于碳酸二甲酯的 O-甲基化
  • 通过多亚甲基链连接，合成 α1-肾上腺素受体拮抗剂
  • 参与 Baylis-Hillman 反应
  • 参与相转移催化的糖基化反应，合成糖基化的类黄酮

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCL3814
SLCF7488
SLBZ8857
066H0962
053K3665

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Sudip Chaudhuri et al.
Biophysical chemistry, 139(1), 29-36 (2008-11-04)
Steady state and time resolved fluorescence spectroscopy have been used to probe microenvironments of the therapeutically active intrinsically fluorescent flavonoid, 7-hydroxyflavone (7-HF), in model membranes consisting of multilamellar phosphatidylcholine liposomes. Additionally, the antioxidant effects of 7-HF against lipid peroxidation have
Wimal Herath et al.
Chemical & pharmaceutical bulletin, 54(3), 320-324 (2006-03-02)
Fermentation of 3-hydroxyflavone (1) with Beauveria bassiana (ATCC 13144) yielded 3,4'-dihdroxyflavone (3), flavone 3-O-beta-D-4-O-methylglucopyranoside (4) and two minor metabolites. 7-Hydroxyflavone (2) was transformed by Nocardia species (NRRL 5646) to 7-methoxyflavone (5) whilst Aspergillus alliaceus (ATCC 10060) converted it to 4',7-dihydroxyflavone
Osamu Kagami et al.
Journal of bioscience and bioengineering, 106(2), 121-127 (2008-09-23)
A central part (amino-acid position 268-397 of 458 amino-acid residues) of the biphenyl dioxygenase large (alpha) subunit, BphA1, from Pseudomonas pseudoalcaligenes strain KF707 was exchanged with the corresponding part of BphA1 from another biphenyl-degrading bacterium, Pseudomonas putida strain KF715, to
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全球贸易项目编号

货号GTIN
H4530-1G04061833795514