L1002
L-亮氨酸甲酯 盐酸盐
98%, for peptide synthesis
别名:
(S)-2-Amino-4-methylpentanoic acid methyl ester hydrochloride, L-Leu-OMe·HCl
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关于此项目
线性分子式:
(CH3)2CHCH2CH(NH2)COOCH3 · HCl
化学文摘社编号:
分子量:
181.66
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
231-375-0
MDL number:
Beilstein/REAXYS Number:
3595133
产品名称
L-亮氨酸甲酯 盐酸盐, 98%
InChI
1S/C7H15NO2.ClH/c1-5(2)4-6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t6-;/m0./s1
InChI key
DODCBMODXGJOKD-RGMNGODLSA-N
SMILES string
Cl[H].COC(=O)[C@@H](N)CC(C)C
assay
98%
form
powder or crystals
optical activity
[α]22/D +13°, c = 2 in H2O
reaction suitability
reaction type: solution phase peptide synthesis
color
white
mp
151-153 °C (lit.)
application(s)
peptide synthesis
Quality Level
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Gautam K Gandhi et al.
ASN neuro, 2(2), e00030-e00030 (2010-04-17)
Sensory and cognitive impairments have been documented in diabetic humans and animals, but the pathophysiology of diabetes in the central nervous system is poorly understood. Because a high glucose level disrupts gap junctional communication in various cell types and astrocytes
Stephanie M Krasnow et al.
Journal of neuroinflammation, 14(1), 133-133 (2017-07-03)
During acute infections and chronic illnesses, the pro-inflammatory cytokine interleukin-1β (IL-1β) acts within the brain to elicit metabolic derangements and sickness behaviors. It is unknown which cells in the brain are the proximal targets for IL-1β with respect to the
Simon M Cool et al.
Stem cells and development, 14(6), 632-642 (2006-01-26)
Therapeutic modalities aimed at bone regeneration are increasingly employing extracellular matrix (ECM) constituents to control bone marrow progenitor cell (BMPC) commitment, growth, and differentiation. However, the precise role these ECM elements play during stem cell differentiation remains unclear. (See also
A Giese et al.
Brain pathology (Zurich, Switzerland), 8(3), 449-457 (1998-07-21)
To elucidate the role played by the prion protein in scrapie pathogenesis, we performed experiments with PrP27-30 isolated from scrapie-infected hamster brains in cell culture and studied in vivo the temporal and spatial correlation between deposition of the disease-associated isoform
P Parenti et al.
Insect biochemistry and molecular biology, 32(7), 719-727 (2002-06-05)
We have identified three methyl esters that have a potent stimulatory effect on the cotransport system responsible for the absorption of most essential amino acids in the silkworm Bombyx mori. L-Leucine methyl ester, the most powerful activator, determined a large
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