L1002
L-亮氨酸甲酯 盐酸盐
98%, for peptide synthesis
别名:
(S)-2-Amino-4-methylpentanoic acid methyl ester hydrochloride, L-Leu-OMe·HCl
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关于此项目
线性分子式:
(CH3)2CHCH2CH(NH2)COOCH3 · HCl
化学文摘社编号:
分子量:
181.66
Beilstein:
3595133
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22
产品名称
L-亮氨酸甲酯 盐酸盐, 98%
质量水平
方案
98%
表单
powder or crystals
旋光性
[α]22/D +13°, c = 2 in H2O
反应适用性
reaction type: solution phase peptide synthesis
颜色
white
mp
151-153 °C (lit.)
应用
peptide synthesis
SMILES字符串
Cl[H].COC(=O)[C@@H](N)CC(C)C
InChI
1S/C7H15NO2.ClH/c1-5(2)4-6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t6-;/m0./s1
InChI key
DODCBMODXGJOKD-RGMNGODLSA-N
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Stephanie M Krasnow et al.
Journal of neuroinflammation, 14(1), 133-133 (2017-07-03)
During acute infections and chronic illnesses, the pro-inflammatory cytokine interleukin-1β (IL-1β) acts within the brain to elicit metabolic derangements and sickness behaviors. It is unknown which cells in the brain are the proximal targets for IL-1β with respect to the
Gautam K Gandhi et al.
ASN neuro, 2(2), e00030-e00030 (2010-04-17)
Sensory and cognitive impairments have been documented in diabetic humans and animals, but the pathophysiology of diabetes in the central nervous system is poorly understood. Because a high glucose level disrupts gap junctional communication in various cell types and astrocytes
D R Brown et al.
Nature, 380(6572), 345-347 (1996-03-28)
The prion protein PrPc is a glycoprotein of unknown function normally found in neurons and glia. It is involved in diseases such as bovine spongiform encephalopathy (BSE), scrapie and Creutzfeldt-Jakob disease. PrPSc, an altered isoform of PrPC that is associated
Kenneth W Kross et al.
Acta oto-laryngologica, 127(5), 532-539 (2007-04-25)
Conclusion. Tumour-associated macrophages (TAMs) in head and neck squamous cell carcinomas (HNSCCs) secrete interleukin 6 (IL-6) and monocyte chemotactic protein (MCP-1) that can be down-regulated by L-leucine-methylester (LLME); however, there is no qualitative difference between function of TAMs and tissue
A Giese et al.
Brain pathology (Zurich, Switzerland), 8(3), 449-457 (1998-07-21)
To elucidate the role played by the prion protein in scrapie pathogenesis, we performed experiments with PrP27-30 isolated from scrapie-infected hamster brains in cell culture and studied in vivo the temporal and spatial correlation between deposition of the disease-associated isoform
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