L1002
L-亮氨酸甲酯 盐酸盐
98%, for peptide synthesis
别名:
(S)-2-Amino-4-methylpentanoic acid methyl ester hydrochloride, L-Leu-OMe·HCl
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关于此项目
线性分子式:
(CH3)2CHCH2CH(NH2)COOCH3 · HCl
化学文摘社编号:
分子量:
181.66
Beilstein:
3595133
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22
产品名称
L-亮氨酸甲酯 盐酸盐, 98%
方案
98%
表单
powder or crystals
旋光性
[α]22/D +13°, c = 2 in H2O
反应适用性
reaction type: solution phase peptide synthesis
颜色
white
mp
151-153 °C (lit.)
应用
peptide synthesis
SMILES字符串
Cl[H].COC(=O)[C@@H](N)CC(C)C
InChI
1S/C7H15NO2.ClH/c1-5(2)4-6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t6-;/m0./s1
InChI key
DODCBMODXGJOKD-RGMNGODLSA-N
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相关类别
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Stephanie M Krasnow et al.
Journal of neuroinflammation, 14(1), 133-133 (2017-07-03)
During acute infections and chronic illnesses, the pro-inflammatory cytokine interleukin-1β (IL-1β) acts within the brain to elicit metabolic derangements and sickness behaviors. It is unknown which cells in the brain are the proximal targets for IL-1β with respect to the
Gautam K Gandhi et al.
ASN neuro, 2(2), e00030-e00030 (2010-04-17)
Sensory and cognitive impairments have been documented in diabetic humans and animals, but the pathophysiology of diabetes in the central nervous system is poorly understood. Because a high glucose level disrupts gap junctional communication in various cell types and astrocytes
D R Brown et al.
Nature, 380(6572), 345-347 (1996-03-28)
The prion protein PrPc is a glycoprotein of unknown function normally found in neurons and glia. It is involved in diseases such as bovine spongiform encephalopathy (BSE), scrapie and Creutzfeldt-Jakob disease. PrPSc, an altered isoform of PrPC that is associated
Kenneth W Kross et al.
Acta oto-laryngologica, 127(5), 532-539 (2007-04-25)
Conclusion. Tumour-associated macrophages (TAMs) in head and neck squamous cell carcinomas (HNSCCs) secrete interleukin 6 (IL-6) and monocyte chemotactic protein (MCP-1) that can be down-regulated by L-leucine-methylester (LLME); however, there is no qualitative difference between function of TAMs and tissue
Simon M Cool et al.
Stem cells and development, 14(6), 632-642 (2006-01-26)
Therapeutic modalities aimed at bone regeneration are increasingly employing extracellular matrix (ECM) constituents to control bone marrow progenitor cell (BMPC) commitment, growth, and differentiation. However, the precise role these ECM elements play during stem cell differentiation remains unclear. (See also
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