N15553
4-硝基儿茶酚
≥96.0%
别名:
1,2-二羟基-4-硝基苯, 对硝基邻苯二酚
质量水平
方案
≥96.0%
表单
powder
mp
173-177 °C (lit.)
SMILES字符串
Oc1ccc(cc1O)[N+]([O-])=O
InChI
1S/C6H5NO4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H
InChI key
XJNPNXSISMKQEX-UHFFFAOYSA-N
基因信息
rat ... Nos1(24598)
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
C Shen et al.
British journal of pharmacology, 153(4), 784-791 (2007-12-12)
Rifampicin has been extensively reported to exacerbate the hepatotoxicity of isoniazid in patients with tuberculosis. However, this was controversially claimed by previous reports using rat models. This study evaluated the effect of rifampicin on isoniazid-induced hepatocyte toxicity by using human
A Chauhan et al.
Journal of applied microbiology, 88(5), 764-772 (2000-05-03)
Pseudomonas cepacia RKJ200 (now described as Burkholderia cepacia) has been shown to utilize p-nitrophenol (PNP) as sole carbon and energy source. The present work demonstrates that RKJ200 utilizes 4-nitrocatechol (NC) as the sole source of carbon, nitrogen and energy, and
Ayelet Fishman et al.
Biotechnology and bioengineering, 87(6), 779-790 (2004-08-27)
After discovering that toluene 4-monooxygenase (T4MO) of Pseudomonas mendocina KR1 oxidizes nitrobenzene to 4-nitrocatechol, albeit at a very low rate, this reaction was improved using directed evolution and saturation mutagenesis. Screening 550 colonies from a random mutagenesis library generated by
Yongjun Liu et al.
Journal of hazardous materials, 181(1-3), 1010-1015 (2010-06-26)
Liquid-phase decomposition of 4-nitrophenol (4-NP) and formation of hydrogen peroxide (H(2)O(2)) induced by contact glow discharge electrolysis (CGDE) were investigated. Experimental results showed that the decays of 4-NP and total organic carbon (TOC) obeyed the first-order and pseudo-first-order reaction kinetics
W Tassaneeyakul et al.
Biochemical pharmacology, 46(11), 1975-1981 (1993-12-03)
The involvement of human cytochrome P450 (CYP) 2E1 in the hydroxylation of 4-nitrophenol (4NP) to 4-nitrocatechol (4NC) has been investigated using cDNA expression and liver microsomal kinetic and inhibitor techniques. 4NP hydroxylation by human liver microsomes and cDNA-expressed human CYP2E1
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