N21200
2-硝基-1,4-苯二胺
95%
别名:
1,4-二氨基-2-硝基苯, 2-硝基对苯二胺
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关于此项目
线性分子式:
O2NC6H3(NH2)2
化学文摘社编号:
分子量:
153.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-164-5
Beilstein/REAXYS Number:
2210195
MDL number:
Assay:
95%
Form:
powder
InChI
1S/C6H7N3O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,7-8H2
InChI key
HVHNMNGARPCGGD-UHFFFAOYSA-N
SMILES string
Nc1ccc(N)c(c1)[N+]([O-])=O
assay
95%
form
powder
Quality Level
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signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
>372.2 °F - Pensky-Martens closed cup
flash_point_c
> 189 °C - Pensky-Martens closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
S Grégoire et al.
Skin pharmacology and physiology, 21(2), 89-97 (2008-01-12)
Percutaneous penetration studies are usually performed in human skin samples set up in a Franz cell device. The ability to perform these studies may depend on the availability of skin samples. Reconstructed skin models are an interesting alternative to overcome
J J Yourick et al.
Toxicology and applied pharmacology, 166(1), 13-23 (2000-06-30)
2-Nitro-p-phenylenediamine (2NPPD) is a dye used in semipermanent and permanent (tinting color) hair dye formulations. National Toxicology Program toxicology and carcinogenesis testing of 2NPPD has raised concerns about its safety. Therefore, we initiated in vitro studies to measure absorption and
I S Grover et al.
Mutation research, 300(1), 1-3 (1993-06-01)
The water and chloroform extracts of guava were tested for their antimutagenicity. The water extract was effective in inactivating the mutagenicity of direct-acting mutagens, e.g., 4-nitro-o-phenylenediamine, sodium azide, and the S9-dependent mutagen, 2-aminofluorene, in the tester strains of Salmonella typhimurium.
Regioselective N-acetylation as a route of nitro-9-phenylenediamine metabolism by rat liver cytosol.
M Nakao et al.
Chemical & pharmaceutical bulletin, 38(9), 2561-2566 (1990-09-01)
Regioselectivity in N-acetylation of nitro-0-phenylenediamine, a widely used hair dye component, by rat liver cytosolic N-acetyltransferases was studied in relation to its substituent effects on enzymatic N-acetylation of mono-substituted anilines. Nitro-p-phenylenediamine was acetylated specifically at the N4-position to afford the
Metabolism of the hair dye component, nitro-p-phenylenediamine, in the rat.
M Nakao et al.
Chemical & pharmaceutical bulletin, 35(2), 785-791 (1987-02-01)
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