N22908
3-硝基丙酸
97%
别名:
β-硝基丙酸, 3-硝基丙酸, 杀牛型结核菌素, 风车藤酸
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
线性分子式:
O2N(CH2)2CO2H
化学文摘社编号:
分子量:
119.08
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-003-0
Beilstein/REAXYS Number:
1759889
MDL number:
Assay:
97%
Form:
crystals
Quality Level
assay
97%
form
crystals
mp
68-70 °C (lit.)
storage temp.
2-8°C
SMILES string
OC(CC[N+]([O-])=O)=O
InChI
1S/C3H5NO4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)
InChI key
WBLZUCOIBUDNBV-UHFFFAOYSA-N
Biochem/physiol Actions
兴奋性神经毒素，证明可引起类似于 Huntington 疾病的脑损伤。
Still not finding the right product?
Explore all of our products under 3-硝基丙酸
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Emmanuel Brouillet et al.
Journal of neurochemistry, 95(6), 1521-1540 (2005-11-23)
Huntington's disease (HD) is a neurodegenerative disorder caused by a mutation in the gene encoding Huntingtin. The mechanisms underlying the preferential degeneration of the striatum, the most striking neuropathological change in HD, are unknown. Of those probably involved, mitochondrial defects
E Brouillet et al.
Current opinion in neurology, 8(6), 469-473 (1995-12-01)
Compelling evidence suggests that a defect in energy metabolism may play a role in the pathogenesis of various degenerative disorders including Parkinson's disease and Huntington's disease. The behavioural and neuropathological consequences in primates of chronic systemic administration of mitochondrial toxins
Wang-Tso Lee et al.
Progress in neurobiology, 72(2), 87-110 (2004-04-06)
Huntington's disease (HD) is an inherited neurodegenerative disease, in which there is progressive motor and cognitive deterioration, and for which the pathogenesis of neuronal death remains controversial. Mitochondrial toxins like 3-nitropropionic acid (3-NP) and malonate, functioning as the inhibitors of