P14815
4-乙氧基苯胺
98%
别名:
对氨基苯乙醚, 4-乙氧基苯胺
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线性分子式:
C2H5OC6H4NH2
化学文摘社编号:
分子量:
137.18
Beilstein:
606666
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
方案
98%
折射率
n20/D 1.559 (lit.)
沸点
250 °C (lit.)
mp
2-5 °C (lit.)
密度
1.065 g/mL at 25 °C (lit.)
SMILES字符串
CCOc1ccc(N)cc1
InChI
1S/C8H11NO/c1-2-10-8-5-3-7(9)4-6-8/h3-6H,2,9H2,1H3
InChI key
IMPPGHMHELILKG-UHFFFAOYSA-N
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警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Sens. 1
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
闪点(°F)
251.6 °F - closed cup
闪点(°C)
122 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
T Lindqvist et al.
Chemical research in toxicology, 4(4), 489-496 (1991-07-01)
4-Ethoxyaniline (p-phenetidine) is oxidized by peroxidases to form several products, one of which is 4-[(4-ethoxyphenyl)imino]-2,5-cyclohexadien-1-one (1). This compound reacts with N-acetylcysteine (NAC) in methanol-phosphate buffers, generating at least four different products. Four major products, 4-[(4-ethoxyphenyl)amino]phenol (2), 3-(N-acetylcystein-S-yl)-4-[(4-ethoxyphenyl)amino]phenol (3), 2,5-bis(N-acetylcystein-S-yl)-4-[(4-ethoxyphenyl)-amino]phenol (4)
Annabel Kuek et al.
Postgraduate medical journal, 83(978), 251-260 (2007-04-04)
Targeted biologic therapies have revolutionised treatment of immune-mediated inflammatory diseases (IMIDs) due to their efficacy, speed of onset and tolerability. The discovery that clinically unrelated conditions, such as rheumatoid arthritis and Crohn's disease, share similar immune dysregulation has led to
R Larsson et al.
Chemico-biological interactions, 60(3), 317-330 (1986-12-01)
The interaction of N-(4-ethoxyphenyl)p-benzoquinone imine (NEPBQI), a metabolite formed during peroxidase catalyzed metabolism of p-phenetidine, with GSH and its effects in isolated rat hepatocytes were investigated. When reacted with GSH NEPBQI formed both a mono- and a diglutathione conjugate as
R Larsson et al.
The Journal of pharmacology and experimental therapeutics, 235(2), 475-480 (1985-11-01)
The metabolism of p-phenetidine in microsomes from rabbit kidney and the metabolism of acetaminophen and p-phenetidine in human kidney microsomes to protein binding metabolites were examined. Microsomal preparations from rabbit kidney medulla catalyzed the irreversible arachidonic acid-dependent binding of p-[14C]phenetidine
J D Baty et al.
Journal of chromatography, 353, 329-337 (1986-02-26)
Liquid chromatographic methods were developed for the study of the in vitro acetylation of the sulphonamide drug sulphamethazine and a series of aniline derivatives. The sensitivity of the methods have allowed data on the activity of the N-acetyltransferase enzyme(s) in
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