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Merck
CN

S6525

对氨基苯磺酰胺

99%

别名:

对氨基苯磺酰胺

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线性分子式:
H2NC6H4SO2NH2
化学文摘社编号:
分子量:
172.20
EC Number:
200-563-4
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
511852
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InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

InChI key

FDDDEECHVMSUSB-UHFFFAOYSA-N

SMILES string

Nc1ccc(cc1)S(N)(=O)=O

assay

99%

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

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Hasan Turkmen et al.
Bioorganic & medicinal chemistry letters, 15(2), 367-372 (2004-12-18)
A series of sulfonamides has been obtained by reacting sulfanilamide or 5-amino-1,3,4-thiadiazole-2-sulfonamide with omega-chloroalkanoyl chlorides, followed by replacement of the omega-chlorine atom with secondary amines. Tails incorporating heterocyclic amines belonging to the morpholine, piperidine and piperazine ring systems have been
Luca Puccetti et al.
Bioorganic & medicinal chemistry letters, 15(9), 2359-2364 (2005-04-20)
The tumor-associated transmembrane carbonic anhydrase (CA, EC 4.2.1.1) isozyme IX (CA IX) is overexpressed in hypoxic tumors and appears to be involved in acidification of the tumor microenvironment, a process correlated with cancer progression and bad prognosis. The acidification may
Isao Nishimori et al.
Bioorganic & medicinal chemistry letters, 15(17), 3828-3833 (2005-07-26)
The inhibition of the last human carbonic anhydrase (CA, EC 4.2.1.1) isozyme (hCA XIV) discovered has been investigated with a series of sulfonamides, including some clinically used derivatives (acetazolamide, methazolamide, ethoxzolamide, dichlorophenamide, dorzolamide, brinzolamide, benzolamide, and zonisamide), as well as
Francesco Mincione et al.
Bioorganic & medicinal chemistry letters, 15(17), 3821-3827 (2005-07-26)
A new series of thioureido-substituted sulfonamides were prepared by reacting 4-isothiocyanato- or 4-isothiocyanatoethyl-benzenesulfonamide with amines, hydrazines, or amino acids bearing moieties that can lead to an enhanced hydrosolubility, such as 2-dimethylamino-ethylamine, fluorine-containing aromatic amines/hydrazines, an aminodiol, heterocyclic polyamines (derivatives of
Vijay K Agrawal et al.
Bioorganic & medicinal chemistry letters, 16(7), 2044-2051 (2006-02-07)
A quantitative Structure-activity relationship study (QSAR) on a set of carbonic anhydrase (CA, EC 4.2.1.1) inhibitors is reported using first-order valence connectivity index ((1)chi(v)). The inhibitory activity against three isozymes CAI, CAII (cystolic forms), and CAIV (membrane bound form), some

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