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Merck
CN

W218405

Sigma-Aldrich

丁羟甲苯

≥99%, FCC, FG

别名:

2,6-二--丁基-4-甲基苯酚, 2,6-二-丁基甲酚, BHT, DBPC, 丁基化羟基甲苯, 丁基羟基甲苯

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线性分子式:
[(CH3)3C]2C6H2(CH3)OH
化学文摘社编号:
分子量:
220.35
FEMA编号:
2184
Beilstein:
1911640
EC 号:
MDL编号:
UNSPSC代码:
12164502
PubChem化学物质编号:
E编号:
E 321
NACRES:
NA.21
Agency:
follows IFRA guidelines
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生物来源

synthetic

质量水平

等级

FG
Fragrance grade
Kosher

Agency

follows IFRA guidelines

管理合规性

EU Regulation 1223/2009
EU Regulation 1333/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.115

蒸汽密度

7.6 (vs air)

蒸汽压

<0.01 mmHg ( 20 °C)

方案

≥99%

表单

powder or crystals

自燃温度

878 °F

沸点

265 °C (lit.)

mp

69-73 °C (lit.)

应用

flavors and fragrances

文件

see Safety & Documentation for available documents

食品过敏原

no known allergens

致敏芳香化合物

no known allergens

性状检查

camphoraceous

SMILES字符串

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

InChI key

NLZUEZXRPGMBCV-UHFFFAOYSA-N

基因信息

human ... CAPN1(823)
rat ... Capn1(29153), Nos1(24598)

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一般描述

丁基化羟基甲苯是一种合成酚类化合物,主要用作食品工业中的抗氧化剂和防腐剂。它可用于防止油脂和含脂肪食物中的脂质氧化。

应用


  • 气味结合蛋白C12在赤拟谷盗对化学试剂反应中的作用: 该论文探讨了BHT对昆虫生物化学的影响,特别是它如何影响害虫中气味结合蛋白的结合亲和力,该研究为制定更有效的害虫控制策略提供了见解(Wang et al., 2024)。

  • 一种新型芳基哌嗪衍生物(LQFM181)在体外和体内模型中对3-硝基丙酸诱导的神经毒性有防护作用。 : 研究将BHT用作研究神经保护剂的比较标准品,强调了其在与氧化应激和神经保护相关的生化途径中的作用(Campos et al., 2024)。

  • 通过单一稳定性指示高效液相色谱法同时测定局部用药物中氟虫腈、氯菊酯及其关键相关物质。: BHT被用作评估药品稳定性和完整性的内标物,证明了其在药物分析中的实用性(Rathnasekara et al., 2024)。

  • 作为抗氧化剂的吡喃并[2,3-c]吡唑稠合螺吲哚连接的1,2,3-三唑:通过抑制α-淀粉酶和DPP4活性来探索其在抗糖尿病药物开发中的用途。: 该研究以BHT为参考抗氧化剂,比较了新合成化合物的功效,为糖尿病治疗的抗氧化剂研究提供了基准(Chahal et al., 2024)。

象形图

Environment

警示用语:

Warning

危险声明

预防措施声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

260.6 °F - open cup

闪点(°C)

127 °C - open cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How much Butylated hydroxytoluene will I receive in the sample size of Product W218405?

    For current sizing, pricing, and availability please contact our Flavors and Fragrances Customer Service at 1-800-227-4563.

  4. What is Product W218405, Butylated hydroxytoluene soluble in?

    Butylated hydroxytoluene is soluble in Ethanol at 100 mg/ml and sonication may be needed. This compound is practically insoluble in water, but freely soluble in vegetable oils, acetone, chloroform and ether.

  5. How should Product W218405, Butylated hydroxytoluene be stored?

    We recommend storing this product at room temperature.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Burdock GA
Encyclopedia of Food and Color Additives, 1, 327-330 (1997)
Safety aspects of food preservatives
Parke DV & Lewis DFV
Food Additives and Contaminants, 9(5), 561-577 (1992)
Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives
Williams GM, et al.
Food And Chemical Toxicology, 37(9), 1027-1038 (1999)
Silvia Carvajal et al.
Scientific reports, 9(1), 12848-12848 (2019-09-08)
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide, ranging from steatosis to non-alcoholic steatohepatitis (NASH). Recently, cerium oxide nanoparticles (CeO2NPs) have emerged as a new antioxidant agent with hepatoprotective properties in experimental liver
A M Vijesh et al.
European journal of medicinal chemistry, 46(11), 5591-5597 (2011-10-05)
In the present study two new series of Hantzsch 1,4-dihydropyridine derivatives (1,4-DHPs) containing substituted pyrazole moiety (4a-f and 5a-f) were synthesized by the reaction of 3-aryl-1H-pyrazole-4-carbaldehydes with 1,3-dicarbonylcompounds (ethylacetoacetate and methylacetoacetate) and ammonium acetate. The newly synthesized compounds were characterized

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