产品名称
3β,7α,25-trihydroxy-5-cholestenoic acid, Avanti Research™ - A Croda Brand 700132P, powder
InChI
1S/C27H44O5/c1-16(6-5-11-27(4,32)24(30)31)19-7-8-20-23-21(10-13-26(19,20)3)25(2)12-9-18(28)14-17(25)15-22(23)29/h15-16,18-23,28-29,32H,5-14H2,1-4H3,(H,30,31)/t16-,18+,19-,20?,21?,22-,23?,25+,26-,27?/m1/s1
InChI key
UOADYMQCTKNNPV-NMRWGJHFSA-N
SMILES string
O[C@H](C1)CC[C@](C1=C[C@H]2O)(C)C3C2C(CC[C@@H]4[C@H](C)CCCC(C)(O)C(O)=O)[C@]4(C)CC3
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700132P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700132P
shipped in
dry ice
storage temp.
−20°C
General description
3β,7α,25-trihydroxy-5-cholestenoic acid is synthesized from 3β, 25-dihydroxy-5-cholestenoic acid in the presence of enzyme 25-hydroxycholesterol 7α-hydroxylase (CYP7B1). It is also synthesized from 7α,25-dihydroxycholesterol by the action of enzyme sterol 27-hydroxylase (CYP27A1).
Biochem/physiol Actions
3β,7α,25-trihydroxy-5-cholestenoic acid is used in the synthesis of 7α,25-dihydroxy-3-oxocholest-4-en-26-oic acid by using cholesterol oxidase.
Packaging
5 mL Amber Glass Screw Cap Vial (700132P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
法规信息
新产品
此项目有
{Identification of 7{alpha
Abdel-Khalik J, et al.
Biochimie, 153, 86-86 (2018)
William J Griffiths et al.
Free radical biology & medicine, 134, 42-52 (2018-12-24)
Using liquid chromatography - mass spectrometry in combination with derivatisation chemistry we profiled the oxysterol and cholestenoic acid content of cerebrospinal fluid from patients with Alzheimer's disease (n = 21), vascular dementia (n = 11), other neurodegenerative diseases (n = 15, Lewy bodies dementia, n = 3, Frontotemporal
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