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关于此项目
经验公式（希尔记法）:
C20H18NO8PD22
化学文摘社编号:
分子量:
475.64
MDL number:
NACRES:
NA.12
UNSPSC Code:
12352211
Assay:
>99% (TLC)
Form:
liquid
产品名称
06:0 PC-d22, Avanti Research™ - A Croda Brand 790427C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (790427C-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 790427C
concentration
10 mg/mL (790427C-10mg)
shipped in
dry ice
storage temp.
−20°C
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General description
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Phosphatidylcholine is a zwitterionic glycerophospholipid, containing choline. It consists of a head and two tails. Head group contains choline and phosphate. Head is polar and water soluble. The tail group contains two fatty acyl chains esterified with glycerol. Tail group is non-polar and water-insoluble. Phosphatidylcholine is synthesized in the liver by phosphatidylethanolamine methyltransferase (PEMT) pathway. It is also synthesized by the Kennedy pathway and the Lands cycle.
Application
06:0 PC-d22 (1,2-dihexanoyl-d22-sn-glycero-3-phosphocholine) has been used:
- as bicelles for lipid in HN-HN nuclear overhauser enhancement (NOE) detection
- as an internal standard in residual algal suspension for liquid chromatography-mass spectrometry analysis (LC-MS/MS)
- to produce bicelles to investigate C-peptide and membrane interaction by diffusion nuclear magnetic resonance (NMR) and 2D total correlation spectroscopy (TOCSY)
Biochem/physiol Actions
Phosphatidylcholine (PC) is a major component of the membrane bilayer. It is involved in the synthesis of signaling molecules. PC is the precursor for the synthesis of sphingomyelin and phosphatidylserine.
Packaging
5 mL Clear Glass Sealed Ampule (790427C-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
新产品
此项目有
Biochemistry of Lipids, Lipoproteins and Membranes (2015)
Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage
Moessinger C, et al.
BMC Cell Biology, 15(1), 43-43 (2014)
Metabolic and morphological changes of an oil accumulating trebouxiophycean alga in nitrogen-deficient conditions
Ito T, et al.
Metabolomics, 9(1), 178-187 (2013)
pH-dependent interaction between C-peptide and phospholipid bicelles
Unnerstaale S and Maler L
Journal of biophysics (Hindawi Publishing Corporation : Online), 2012(1), 43-43 (2012)
The unusual transmembrane partition of the hexameric channel of the hepatitis C virus
Chen W, et al.
Structure, 26(4), 627-634 (2018)
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