产品名称
DC-Chol/DOPE混合物, Avanti Research™ - A Croda Brand 790625C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (790625C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 790625C
concentration
10 mg/mL (790625C-25mg)
lipid type
cationic lipids
shipped in
dry ice
storage temp.
−20°C
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General description
DC-Chol/DOPE blend is a cationic lipid blend.
DC-Chol/DOPE is a blend of a cationic lipid : 3b-[N-(N′, N′ dimethyl-aminoethane)carbomyl] (DC-Chol ) and a neutral lipid : dioleoyl phosphatidylethanolamine (DOPE).
Biochem/physiol Actions
The DC-Chol/DOPE blend is widely useful in liposome preparation as it influences the process of encapsulation. 1:2 or 3:2 is a preferred molar ratio for DC-Chol/DOPE liposomes.
Packaging
5 mL Clear Glass Sealed Ampule (790625C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease
Leone P, et al.
Annals of Neurology, 48(1), 27-38 (2000)
Shuoye Yang et al.
International journal of pharmaceutics, 434(1-2), 155-160 (2012-05-31)
Three most commonly used preparative methods, dry-film, reverse phase evaporation and ethanol injection were employed to prepare cationic liposomes composed of DC-Chol and DOPE, respectively. The resulting samples were contrasted through morphology observation, particle size and zeta potential analysis. Sephadex
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