登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C26H45D7NO7P
化学文摘社编号:
分子量:
528.71
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141825
Assay:
>99% (TLC)
Form:
liquid
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (791643C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
1 mg/mL (791643C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
18:1-d7 Lyso PC 1油酰基(d7)-2-羟基-sn-甘油-3-磷酸胆碱是氘代磷脂。该脂质溶血磷脂酰胆碱是以油酸酯化。油酸包含氘离子。溶血磷脂酰胆碱（LPC） 是在磷脂酶 A2 的作用下由磷脂酰胆碱衍生而来。
这种氘标记的脂质也可用于多种脂质标准品制剂中。SPLASH™ LIPIDOMIX™ 标准品包括与人血浆的所有主要脂质类别对应的脂质，从而实现一种简单的内标溶液适用每种样品。
Application
18:1-d7 Lyso PC 已用于:
- 作为高效液相色谱电喷雾电离串联质谱（HPLC-ESIMS/MS） 的内标物，用于来源于骨髓的巨噬细胞的脂质组学分析
- 作为提取溶剂的成分，用于从生物样品中分离脂质
- 作为液相色谱串联质谱（LC-MS/MS）中血清样品的内标物
Biochem/physiol Actions
溶血磷脂酰胆碱（LPC）。LPC 水平升高与糖尿病和心血管疾病有关。LPC 刺激细胞因子并与过敏性疾病有关。它还导致膜上的裂解。
Packaging
5 mL透明玻璃密封安瓿（791643C-1mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Preeti Bansal et al.
Scientific reports, 6, 27430-27430 (2016-06-11)
Phospholipase A2 (sPLA2), pivotal for allergic and inflammatory response, hydrolyses phosphatidylcholine (PC) to lysophosphatidylcholine (LPC). In present study, the role of LPC in allergic airway disease manifestation was studied using mouse model. Balb/c mice were immunized using cockroach extract (CE)
Shi-Hui Law et al.
International journal of molecular sciences, 20(5) (2019-03-09)
Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively associated with cardiovascular and neurodegenerative diseases. However, findings from recent clinical lipidomic studies of LPC have been controversial. A key issue is the complexity of the enzymatic cascade involved in
Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 791643C-1MG | 04061837665929 |