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关于此项目
经验公式(希尔记法):
C25H48N3O7P
化学文摘社编号:
分子量:
533.64
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
N-P Tyrosine PA, Avanti Research™ - A Croda Brand 800725P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (800725P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 800725P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
General description
Lysophosphatidic acid (LPA) receptor modulators include N-palmitoyl serine phosphoric acid and N-palmitoyl-tyrosine phosphoric acid. N-palmitoyl serine phosphoric acid and N-palmitoyl-tyrosine phosphoric acid are competitive inhibitors of the LPA receptor in Xenopus oocytes. However, in mammalian cells, N-palmitoyl-tyrosine phosphoric acid may act as an agonist for the LPA receptor. LPA is a lipid mediator that acts similar to growth factors through G-protein coupled plasma membrane receptors. LPA may play a role in platelet aggregation, smooth muscle contraction, vasoactive changes, cytoskeletal reorganization and cell proliferation.
Packaging
5 mL Amber Glass Screw Cap Vial (800725P-1mg)
Preparation Note
Product use: N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acid can be used for cell studies. dissolved these lipids in 0.1 mL PBS containing 0.1 mg/mL human serum albumin before adding to cells. In X. laevis studies, these LPA inhibitors were dissolved in DMSO at 1 mM and filtered through a 0.45 mM membrane filter before injection.
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids