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关于此项目
经验公式（希尔记法）:
C40H71N6O13P
化学文摘社编号:
分子量:
875.00
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
16:0-12:0 NBD PS, Avanti Research™ - A Croda Brand 810193C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810193C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810193C
concentration
1 mg/mL (810193C-1mg)
shipped in
dry ice
storage temp.
−20°C
Application
16:0-06:0 NBD PS or 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) may be used in the liposome preparation for in vitro assay of the phosphatidylethanolamine (PE) production by determining the phosphatidylserine decarboxylase 1 (Psd1p) activity.
Biochem/physiol Actions
Phosphatidylserine (PS) regulates numerous enzymes and structural components maintains the nerve cell membrane and myelin sheath.
General description
Phosphoserine (PS) is present in the intracellular membranes and grey matter, and isenriched in the cytosolic leaflet of plasma membrane. NBD PS is a fluorescently labelled lipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.
Packaging
5 mL Amber Glass Screw Cap Vial (810193C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Yasushi Tamura et al.
The Journal of biological chemistry, 287(52), 43961-43971 (2012-11-06)
Phosphatidylethanolamine (PE) plays important roles for the structure and function of mitochondria and other intracellular organelles. In yeast, the majority of PE is produced from phosphatidylserine (PS) by a mitochondrion-located PS decarboxylase, Psd1p. Because PS is synthesized in the endoplasmic
Jean E Vance et al.
Progress in lipid research, 44(4), 207-234 (2005-06-28)
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and enzymes that are involved in PS biosynthesis in bacteria, yeast, plants and mammalian cells and discuss
Ouma Onguka et al.
The Journal of biological chemistry, 290(20), 12744-12752 (2015-04-02)
Phosphatidylethanolamine (PE) is a major cellular phospholipid that can be made by four separate pathways, one of which resides in the mitochondrion. The mitochondrial enzyme that generates PE is phosphatidylserine decarboxylase 1 (Psd1p). The pool of PE produced by Psd1p
Michael J Glade et al.
Nutrition (Burbank, Los Angeles County, Calif.), 31(6), 781-786 (2015-05-03)
The aim of this study was to assess the roles and importance of phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain biochemistry, physiology, and function. A scientific literature search was conducted on MEDLINE for relevant articles regarding
Soumi Mukherjee et al.
Chemistry and physics of lipids, 127(1), 91-101 (2004-01-07)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. NBD-labeled lipids have previously been used to monitor the organization and
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