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Merck
CN

810193P

Avanti

16:0-12:0 NBD PS

Avanti Research - A Croda Brand

别名:

1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt)

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关于此项目

经验公式(希尔记法):
C40H71N6O13P
化学文摘社编号:
分子量:
875.00
UNSPSC代码:
12352211
NACRES:
NA.25
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产品名称

16:0-12:0 NBD PS, Avanti Research - A Croda Brand 810193P, powder

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 1 mg (810193P-1mg)
pkg of 5 × 1 mg (810193P-5mg)

制造商/商品名称

Avanti Research - A Croda Brand 810193P

运输

dry ice

储存温度

−20°C

一般描述

Phosphatidylserine (PS) is a membrane phospholipid comprising 2-10% of total phospholipids. It is majorly localized on the inner leaflet of plasma membrane. NBD PS contains the fluorophore, 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) labelled at the headgroup of PS.

应用

16:0-12:0 NBD PS might be used in a liposome for determination of phosphatidylethanolamine (PE) production by the phosphatidylserine decarboxylase 1 (Psd1p) activity assay.

生化/生理作用

Phosphatidylserine (PS) is involved in the signaling of the coagulation cascade for homeostasis. It is involved in maintaining the nerve cell membrane and myelin sheath.

包装

5 mL Amber Glass Screw Cap Vial (810193P-1mg)
5 mL Amber Glass Screw Cap Vial (810193P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

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Yasushi Tamura et al.
The Journal of biological chemistry, 287(52), 43961-43971 (2012-11-06)
Phosphatidylethanolamine (PE) plays important roles for the structure and function of mitochondria and other intracellular organelles. In yeast, the majority of PE is produced from phosphatidylserine (PS) by a mitochondrion-located PS decarboxylase, Psd1p. Because PS is synthesized in the endoplasmic
Jean E Vance et al.
Progress in lipid research, 44(4), 207-234 (2005-06-28)
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and enzymes that are involved in PS biosynthesis in bacteria, yeast, plants and mammalian cells and discuss
Ouma Onguka et al.
The Journal of biological chemistry, 290(20), 12744-12752 (2015-04-02)
Phosphatidylethanolamine (PE) is a major cellular phospholipid that can be made by four separate pathways, one of which resides in the mitochondrion. The mitochondrial enzyme that generates PE is phosphatidylserine decarboxylase 1 (Psd1p). The pool of PE produced by Psd1p
Michael J Glade et al.
Nutrition (Burbank, Los Angeles County, Calif.), 31(6), 781-786 (2015-05-03)
The aim of this study was to assess the roles and importance of phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain biochemistry, physiology, and function. A scientific literature search was conducted on MEDLINE for relevant articles regarding
Soumi Mukherjee et al.
Chemistry and physics of lipids, 127(1), 91-101 (2004-01-07)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. NBD-labeled lipids have previously been used to monitor the organization and

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