810241P
Avanti
TopFluor™ TMR PE
Avanti Research™ - A Croda Brand
别名:
1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phosphoethanolamine
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关于此项目
经验公式（希尔记法）:
C50H76 BF2N4 O10P
CAS Number:
分子量:
972.94
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
Product Name
TopFluor™ TMR PE, Avanti Research™ - A Croda Brand 810241P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810241P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810241P
运输
dry ice
储存温度
−20°C
一般描述
Phosphoethanolamine contains a phosphate group linked with the second carbon of ethanolamine.
生化/生理作用
Phosphoethanolamine (PEA) is a precursor to phosphatidylethanolamine and phosphatidylcholine, involved in the biosynthesis of cell membrane. In human body, PEA is a product of degradation of sphingosine phosphate and endocannabinoid anandamide. PEA has potential cytotoxic properties and is known to induce the caspase-independent cell death. PEA is capable of inhibiting tumor growth in vitro and in vivo in mouse models.
包装
5 mL Amber Glass Screw Cap Vial (810241P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
法规信息
新产品
Lisley I Mambelli et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 103, 18-28 (2018-04-11)
Phosphoethanolamine (PEA) is a fundamental precursor during the biosynthesis of cell membranes phospholipids. In the past few years, it has been described as a potential antitumor agent. In previous studies, we demonstrated that PEA showed antitumor properties in vitro and
Noam Pondé et al.
Ecancermedicalscience, 10, 681-681 (2016-12-03)
The use of unproven forms of therapy in cancer treatment is very common. In Brazil, the distribution by researchers to patients of an investigational agent called phophoethanolamine (PHOS) has led to a widely publicized scientific scandal. PHOS is a precursor
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
Ann C Kimble-Hill et al.
The journal of physical chemistry. B, 122(35), 8404-8415 (2018-06-08)
Phosphatidylinositol (PI) lipids are necessary for many cellular signaling pathways of membrane associated proteins, such as angiomotin (Amot). The Amot family regulates cellular polarity, growth, and migration. Given the low concentration of PI lipids in these membranes, it is likely
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