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关于此项目
经验公式（希尔记法）:
C63H105 BF2N2O6
化学文摘社编号:
分子量:
1035.33
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
18:1-18:1-C11 TopFluor™ TG, Avanti Research™ - A Croda Brand 810298C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810298C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810298C
concentration
1 mg/mL (810298C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
Lipid droplets (LDs) are organelles that store lipids as reservoirs of metabolic energy and membrane lipid precursors, and they have been identified in the nucleus of some cells. LDs can be found in most eukaryotic cells. Most prominent are LDs in adipocytes, which make up most of the cellular volume, but other metabolically active cell types, such as liver or muscle cells, also have abundant LDs. LDs are unusual organelles in that they are bound by a monolayer of surface phospholipids, into which specific proteins are embedded, such as perilipins and metabolic enzymes. The cell biology of LDs as cellular organelles is only beginning to be unraveled. Avanti now offers a series of fluorescently-labeled mono-, di-, and triglycerides, which are useful for studying these important cellular organelles.
Application
18:1-18:1-C11TopFluor™ TG (1,2-dioleoyl-3-[11-(dipyrrometheneboron difluoride)undecanoyl]-sn-glycerol) has been used as a standard to validate fluorescent lipid bands in fatty acid incorporation assay. It may also be used in fluorescent lipid synthesis.
Packaging
5 mL Clear Glass Sealed Ampule (810298C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Hanaa Hariri et al.
The Journal of cell biology, 218(4), 1319-1334 (2019-02-28)
Lipid droplets (LDs) serve as cytoplasmic reservoirs for energy-rich fatty acids (FAs) stored in the form of triacylglycerides (TAGs). During nutrient stress, yeast LDs cluster adjacent to the vacuole/lysosome, but how this LD accumulation is coordinated remains poorly understood. The
Øystein Sæle et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1863(9), 948-957 (2018-05-21)
The zebrafish larva is a powerful tool for the study of dietary triglyceride (TG) digestion and how fatty acids (FA) derived from dietary lipids are absorbed, metabolized and distributed to the body. While fluorescent FA analogues have enabled visualization of
Robert V Farese et al.
Cell, 139(5), 855-860 (2009-12-01)
Long underappreciated as important cellular organelles, lipid droplets are finally being recognized as dynamic structures with a complex and interesting biology. In light of this newfound respect, we discuss emerging views on lipid droplet biology and speculate on the major
Yuki Ohsaki et al.
The Journal of cell biology, 212(1), 29-38 (2016-01-06)
Lipid droplets (LDs) in the nucleus of hepatocyte-derived cell lines were found to be associated with premyelocytic leukemia (PML) nuclear bodies (NBs) and type I nucleoplasmic reticulum (NR) or the extension of the inner nuclear membrane. Knockdown of PML isoform
Robert V Farese et al.
The Journal of cell biology, 212(1), 7-8 (2016-01-06)
Lipid droplets (LDs) are sometimes found in the nucleus of some cells. In this issue, Ohsaki et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507122) show that the nuclear membrane, promyelocytic leukemia bodies, and the protein PML-II play a role in nuclear
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