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830843C

Avanti

10:0 PA

Avanti Research™ - A Croda Brand

别名:

PA(10:0/10:0)

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About This Item

经验公式（希尔记法）:
C23H44O8PNa
CAS Number:
321883-64-1
分子量:
502.55
MDL编号:
MFCD03788002
UNSPSC代码:
51191904
NACRES:
NA.25

Product Name

10:0 PA, 1,2-didecanoyl-sn-glycero-3-phosphate (sodium salt), chloroform

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (830843C-25mg)
pkg of 1 × 20 mL (830843C-500mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 830843C

浓度

10 mg/mL (830843C-25mg)
25 mg/mL (830843C-500mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O.[Na+]

InChI

1S/C23H45O8P.Na/c1-3-5-7-9-11-13-15-17-22(24)29-19-21(20-30-32(26,27)28)31-23(25)18-16-14-12-10-8-6-4-2;/h21H,3-20H2,1-2H3,(H2,26,27,28);/q;+1/p-1/t21-;/m1./s1

InChI key

YVHWEENUNNUSBE-ZMBIFBSDSA-M

相关类别

一般描述

Phosphatidic acid (PA) is a diacyl-glycerophospholipid. With the help of ester linkage, two fatty acids and a phosphate group are attached to a glycerol molecule through covalent bonds. PA is rich in soy lecithin. It can be produced through phosphorylation of diacyl glycerol (DAG) with the help of diacylglycerol kinases (DGKs).

应用

10:0 PA has been used for preparation of the ubiquitin specific peptidase 1-mitochondrial distribution and morphology protein 35 (Ups1–Mdm35)– phosphatidic acid (PA) complex.
It may be used:
  • as a component in the lipid bilayer to study how lipid geometry acts in coat protein I (COPI) vesicle fission
  • to study its effects on intracellular Ca2+ concentration ([Ca2+]i) in C6 rat glioma and L2071 mouse fibroblast cells
  • to activate protein kinase C (PKC) in chinese hamster ovary (CHO) cells

生化/生理作用

Phosphatidic acid (PA) is present in biomembranes. It is the precursor for other phospholipids and acts as a signaling molecule. PA is implicated in nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) activity. 10:0 PA along with 1-oleoyl-2-acetoyl-sn-glycerol (OAG) and arachidonic acid (AA) can be used as cell-free activators to promote NADPH oxidase activity.

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (830843C-500mg)
5 mL Clear Glass Sealed Ampule (830843C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

WGK

WGK 3

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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