SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
InChI key
JLPULHDHAOZNQI-ZTIMHPMXSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (840054P-1g), pkg of 2 × 100 mg (840054P-200mg), pkg of 5 × 100 mg (840054P-500mg), pkg of 1 × 25 mg (840054P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
phospholipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
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General description
磷脂酰胆碱（PC）是质膜的主要成分。通常来说，无论是来自人类还是植物，PC都含有不饱和脂肪酸。大豆PC的脂肪酸成分中有70%为亚麻酸。因此，大豆PC在含水体系中具有较低的相变温度。
Application
大豆PC已被用于制备脂质体。大豆PC适用于制备柔性脂质体（FLUV）和治疗嗜铬细胞瘤（PC12）细胞，以分析其对胞吐动力学的影响。
Biochem/physiol Actions
磷脂酰胆碱是磷酸胆碱的主要来源，其可有助于将神经酰胺转化为鞘磷脂。磷脂酰胆碱在活组织中比例更高。大豆PC常用于化妆品配方中。
Packaging
5 mL透明玻璃密封安瓿（840054P-200mg）
5 mL透明玻璃密封安瓿（840054P-25mg）
5 mL透明玻璃密封安瓿（840054P-500mg）
60 mL棕色广口螺旋盖玻璃瓶（840054P-1g）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
Handbook of Cosmetic Science and Technology, 1151(1), 155-155 (2005)
Phospholipid mediated plasticity in exocytosis observed in PC12 cells.
Uchiyama Y, et al.
Brain Research, 1151(1), 46-54 (2007)
María Cecilia Izquierdo et al.
Journal of cosmetic dermatology (2020-04-14)
Ultradeformable liposomes are promising carriers for cosmeceutical actives as they can be loaded with molecules of different polarities, and they present unique penetration properties. While those features have already been tested, we wanted to know whether their special penetration properties
Min S Wang et al.
Soft matter, 8(30), 7909-7918 (2013-09-13)
It has been reported that the oxidation of phosphatidylcholine (PC) is necessary for C-reactive protein (CRP) to bind to lipid membranes, but it remains elusive why CRP only binds oxidized membranes. Here we offer a new perspective on the role
Barbara Bianca Gerbelli et al.
Langmuir : the ACS journal of surfaces and colloids, 34(5), 2171-2179 (2017-12-29)
In the present work, we investigate the effect of two short phenylalanine-based peptides on lipid membranes. A simplified model membrane composed of lecithin vesicles was used to incorporate different amounts of the two amino acid sequences, the dimmer l,l-diphenylallanine (FF)
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