产品名称
E. coli PG, Avanti Research™ - A Croda Brand 841188C
方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 1 mL (841188C-10mg)
pkg of 1 × 2.5 mL (841188C-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 841188C
浓度
10 mg/mL (841188C-10mg)
10 mg/mL (841188C-25mg)
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCCC(C1)C1CCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
一般描述
Phosphatidylglycerol (PG) is a membrane lipid found in the inner membrane of E. coli.
应用
E. coli PG or L-α-phosphatidylglycerol (E. coli) (sodium salt) might be used:
- as a lipid antigen to trigger human T cell response
- as a standard in mass spectrometry analysis of mammalian cell entry (MCE) proteins bound to phosphatidylglycerol (PG)
- n bacterial model membranes to evaluate the lipid-lipid interactions to serve potentially as a model for validation of novel antibacterial agents
包装
5 mL Clear Glass Sealed Ampule (841188C-10mg)
5 mL Clear Glass Sealed Ampule (841188C-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Adam Shahine et al.
Science immunology, 2(16) (2017-10-22)
Human T cell autoreactivity toward lipid antigens presented by CD1 proteins can manifest in numerous diseases, including psoriasis, contact hypersensitivities, and allergies. However, the molecular mechanisms for regulating T cell autoreactivity toward lipid antigens remain unclear. We determined the basis
Damian C Ekiert et al.
Cell, 169(2), 273-285 (2017-04-08)
How phospholipids are trafficked between the bacterial inner and outer membranes through the hydrophilic space of the periplasm is not known. We report that members of the mammalian cell entry (MCE) protein family form hexameric assemblies with a central channel
Mikhail Bogdanov et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(34), 15057-15062 (2010-08-11)
Phosphatidylcholine (PC) has been widely used in place of naturally occurring phosphatidylethanolamine (PE) in reconstitution of bacterial membrane proteins. However, PC does not support native structure or function for several reconstituted transport proteins. Lactose permease (LacY) of Escherichia coli, when
Javier Hoyo et al.
General physiology and biophysics, 39(2), 195-202 (2020-04-25)
The current strategies to eradicate bacteria require that the antimicrobial agent either penetrate or disrupt the bacterial membrane. In Escherichia coli (E.coli) as a model of Gram-negative strains, the antimicrobials have to cross two barriers - the outer and the
Ildiko Van Rhijn et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(2), 380-385 (2015-12-02)
In contrast with the common detection of T cells that recognize MHC, CD1a, CD1c, or CD1d proteins, CD1b autoreactive T cells have been difficult to isolate in humans. Here we report the development of polyvalent complexes of CD1b proteins and
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