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关于此项目
经验公式（希尔记法）:
C25H58N3O19P3
化学文摘社编号:
分子量:
797.66
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
08:0 PI(3,5)P2, 1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt), powder
SMILES string
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 μg (with stopper and crimp cap (850184P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850184P-500ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 850184P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
General description
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is the least found phosphoinositides (PIs) and it accounts for approximately 0.05 to 0.1% of total cellular PI.
Biochem/physiol Actions
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) plays a key role in the embryonic development. It is very essential at postnatal stages. It is capable of activating ion channels on endosomes and lysosomes.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (850184P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850184P-500ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Junya Hasegawa et al.
Cell structure and function, 42(1), 49-60 (2017-03-18)
In most eukaryotes, phosphoinositides (PIs) have crucial roles in multiple cellular functions. Although the cellular levels of phosphatidylinositol 5-phosphate (PI5P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) are extremely low relative to some other PIs, emerging evidence demonstrates that both lipids are crucial
Bong-Kwan Han et al.
The Journal of biological chemistry, 288(28), 20633-20645 (2013-06-05)
Glucose/carbon metabolism is a fundamental cellular process in living cells. In response to varying environments, eukaryotic cells reprogram their glucose/carbon metabolism between aerobic or anaerobic glycolysis, oxidative phosphorylation, and/or gluconeogenesis. The distinct type of glucose/carbon metabolism that a cell carries
Gerald R V Hammond et al.
Science (New York, N.Y.), 337(6095), 727-730 (2012-06-23)
The quantitatively minor phospholipid phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P(2)] fulfills many cellular functions in the plasma membrane (PM), whereas its synthetic precursor, phosphatidylinositol 4-phosphate (PI4P), has no assigned PM roles apart from PI(4,5)P(2) synthesis. We used a combination of pharmacological and chemical
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