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关于此项目
经验公式(希尔记法):
C42H84NO8P
化学文摘社编号:
分子量:
762.09
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
17:0 PC, 1,2-diheptadecanoyl-sn-glycero-3-phosphocholine, powder
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3
InChI key
RTWAYAIMWLNAJW-UHFFFAOYSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (850360P-200mg), pkg of 1 × 25 mg (850360P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850360P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
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General description
Avanti提供的磷脂酰胆碱产品列表旨在提供具有多种物理性质的化合物。可选产品包括短链(C3-C8是水溶性和吸湿性的)、饱和、多不饱和和混合酸PC。′所有产品均通过HPLC纯化,并采取特殊预防措施保护产品不发生氧化和水解。
磷脂酰胆碱(PC)是在膜中大量分布的磷脂。磷脂酰胆碱sn-1和sn-2位的脂肪酸通过酯键与甘油共价连接。
Application
17:0 PC(1,2-双十七烷酰-sn-甘油-3-磷酸胆碱)已用作:
- 作为脂肪酸分析中的磷脂内标
- 作为从冷冻叶组织中提取脂质的提取混合液组分
- 作为内标和甲醇:甲基叔丁基醚(MTBE)提取缓冲液组分,用于通过气相色谱-质谱(GC-MS)法测定肿瘤和正常组织中的代谢水平
Biochem/physiol Actions
磷脂酰胆碱(PC)是类花生酸的主要来源。
Packaging
5 mL棕色玻璃螺旋盖样品瓶(850360P-200mg)
5 mL棕色玻璃螺旋盖样品瓶(850360P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
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Metabolic reprogramming is one of the hallmarks of renal cell cancer (RCC). We hypothesized that altered metabolism of RCC cells results from dysregulation of microRNAs targeting metabolically relevant genes. Combined large-scale transcriptomic and metabolic analysis of RCC patients tissue samples
Kristin A Marks et al.
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Krista D Sowell et al.
Journal of the American College of Nutrition, 39(3), 249-260 (2020-04-03)
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