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850368P

Avanti

20:0 PC

Avanti Research - A Croda Brand

别名:

1,2-dieicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/20:0)

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25 MG
¥815.23
100 MG
¥2,744.98

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25 MG
¥815.23
100 MG
¥2,744.98

About This Item

经验公式(希尔记法):
C48H96NO8P
CAS Number:
分子量:
846.25
MDL编号:
UNSPSC代码:
51191904
NACRES:
NA.25

¥815.23


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Product Name

20:0 PC, 1,2-diarachidoyl-sn-glycero-3-phosphocholine, powder

方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 200 mg (850368P-200mg)
pkg of 1 × 25 mg (850368P-25mg)
pkg of 1 × 500 mg (850368P-500mg)

制造商/商品名称

Avanti Research - A Croda Brand 850368P

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C48H96NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h46H,6-45H2,1-5H3/t46-/m1/s1

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此商品
76183PHR1455Y0000800
biological source

synthetic

biological source

synthetic

biological source

-

biological source

synthetic

assay

95.0-100.5%

assay

≥99.0% (RT)

assay

-

assay

-

form

powder

form

powder

form

-

form

solid

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

-

color

light yellow

color

white to faint yellow

color

-

color

-

一般描述

Phosphatidylcholine, a major source of diacylglycerol (DAG) is considered as a biological membrane lipid.[1] 20:0 PC is a zwitterionic lipid.[2]
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

应用

20:0 PC may be used:
  • in the preparation of liposomes[2]
  • to prepare vesicles or supported bilayer to study its ability in spontaneously forming distinct lipid domains, rafts and/or asymmetric bilayers along with other phosphatidylcholine lipids[3]
  • to prepare small unilamellar vesicles (SUVs) to study the effect of hydrophobic mismatch on gramicidin conformation and organization[4]

生化/生理作用

Phosphatidylcholine (PC) can serve as a surfactant in the mucus.[5]

包装

20 mL Clear Glass Screw Cap Vial (850368P-500mg)
5 mL Amber Glass Screw Cap Vial (850368P-200mg)
5 mL Amber Glass Screw Cap Vial (850368P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    Journal of the American College of Cardiology, 62(17), 1580-1584 (2013-08-07)
    This study sought to examine the relationship between niacin treatment, lipoproteins, and cardiovascular (CV) outcomes in this secondary analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes) trial. During a
    Koon K Teo et al.
    Stroke, 44(10), 2688-2693 (2013-07-25)
    In Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial, addition of extended-release niacin (ERN) to simvastatin in participants with established cardiovascular disease, low high-density lipoprotein cholesterol, and high triglycerides had no incremental
    Paul M Lavigne et al.
    Journal of the American College of Cardiology, 61(4), 440-446 (2012-12-26)
    This study sought to assess the efficacy of niacin for reducing cardiovascular disease (CVD) events, as indicated by the aggregate body of clinical trial evidence including data from the recently published AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High
    Beat Müller et al.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20(2), 181-195 (2003-10-11)
    A novel methodology for establishing a pharmacological dose-effect relationship of methyl nicotinate, hexyl nicotinate and nicotinic acid acting as peripheral vasodilators in the skin following topical application is investigated. This methodology involves the estimation of the unbound drug concentration in
    Martina Lukasova et al.
    Trends in pharmacological sciences, 32(12), 700-707 (2011-09-29)
    Nicotinic acid (niacin) has been used for decades to prevent and treat atherosclerosis. The well-documented antiatherogenic activity is believed to result from its antidyslipidemic effects, which are accompanied by unwanted effects, especially a flush. There has been renewed interest in

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