产品名称
18:0-16:0 PC, 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine, chloroform
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850465C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850465C
concentration
10 mg/mL (850465C-25mg)
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
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General description
Phosphatidylcholines (PCs) are amphipathic molecules, which accounts for approximately 40−50% of the total cellular phospholipids. 18:0-16:0 PC (1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine) is an asymmetric lipid.
Application
18:0-16:0 PC (1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
- in bilayer membranes to study the thermodynamic properties of phase transitions
- as a carrier in unilamellar vesicles to evaluate the fragmentation of hydroperoxy endoperoxide 13-HP-Endo-PC in a model membrane
- as a lipid standard in liquid chromatography−mass spectrometry analysis
Biochem/physiol Actions
Phosphatidylcholine (PC) has the ability to block the penetrance of bacteria by acting as a surfactant.
Packaging
5 mL Clear Glass Sealed Ampule (850465C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
新产品
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Inflammatory Bowel Disease
Parian AM, et al.
Integrative Medicine, 501-516 (2018)
Xiaodong Gu et al.
Chemical research in toxicology, 24(7), 1080-1093 (2011-05-17)
Biologically active phospholipids that incorporate an oxidatively truncated acyl chain terminated by a γ-hydroxyalkenal are generated in vivo. The γ-hydroxyalkenal moiety protrudes from lipid bilayers like whiskers that serve as ligands for the scavenger receptor CD36, fostering endocytosis, e.g., of
Masaki Goto et al.
Biochimica et biophysica acta, 1778(4), 1067-1078 (2008-01-15)
The bilayer phase transitions of palmitoylstearoyl-phosphatidylcholine (PSPC), diheptadecanoyl-PC (C17PC) and stearoylpalmitoyl-PC (SPPC) which have the same total carbon numbers in the two acyl chains were observed by differential scanning calorimetry and high-pressure optical method. As the temperature increased, these bilayers
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features
Jelske N van der Veen et al.
Biochimica et biophysica acta. Biomembranes, 1859(9 Pt B), 1558-1572 (2017-04-16)
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co-workers performed groundbreaking research that established the general outline of many of the pathways of phospholipid biosynthesis. In recent
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