产品名称
18:1 Monomethyl PE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-methyl, powder
SMILES string
[H][C@@](COP([O-])(OCC[N+](C)([H])[H])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
InChI
1S/C42H80NO8P/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43-3)51-42(45)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2/h18-21,40,43H,4-17,22-39H2,1-3H3,(H,46,47)/b20-18+,21-19+/t40-/m1/s1
InChI key
LPXFOQGBESUDAX-KFVQOHGZSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (850850P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850850P
shipped in
dry ice
storage temp.
−20°C
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General description
18:1 Monomethyl phosphoethanolamine (PE) is an alkyl phosphate derivative. Methyl transferases catalyzes the formation of monomethyl PE by acting on PE. It might be involved in the transduction of biochemical signals via the cell membrane.
Application
18:1 Monomethyl PE may be used for the preparation of standard liposomes. It is also suitable to study its effect on the interaction of fructan with monomolecular lipid system.
Packaging
5 mL Clear Glass Sealed Ampule (850850P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Membrane Fluidity (2012)
Effects of lipids on the interaction of SecA with model membranes
Ahn T, et al.
Archives of Biochemistry and Biophysics, 395(1), 14-20 (2001)
Grzegorz Pawlik et al.
The Journal of biological chemistry, 295(8), 2473-2482 (2020-01-15)
Phospholipid N-methyltransferases (PLMTs) synthesize phosphatidylcholine by methylating phosphatidylethanolamine using S-adenosylmethionine as a methyl donor. Eukaryotic PLMTs are integral membrane enzymes located in the endoplasmic reticulum (ER). Recently Opi3, a PLMT of the yeast Saccharomyces cerevisiae was proposed to perform in
Structural requirements of the fructan-lipid interaction
Vereyken IJ, et al.
Biophysical Journal, 84(5), 3147-3154 (2003)
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