Product Name
(R)-FTY720-OMe, (R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol, neat oil
方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 1 mg (857392O-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 857392O
脂质类型
sphingolipids
bioactive lipids
运输
dry ice
储存温度
−20°C
一般描述
(R)-FTY720-OMe is the analogue of FTY720.
(R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity.
生化/生理作用
(R)-FTY720-OMe helps to block DNA synthesis and actin rearrangement induced by sphingosine 1-phosphate (S1P) in MCF-7 breast cancer cells. It can also reduce sphingosine kinase 2 (SK2) expression and prevent DNA synthesis in HEK 293 cells. (R)-FTY720-OMe has anti-breast cancer potential.
包装
5 mL Amber Glass Screw Cap Vial (857392O-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
10 - Combustible liquids
WGK
WGK 3
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