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Merck
CN

857465W

Avanti

AEA-d4

Avanti Research - A Croda Brand

别名:

5Z,8Z,11Z,14Z-eicosatetraenoylethanolaminde-d4

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关于此项目

经验公式(希尔记法):
C22H33 D4NO2
CAS Number:
分子量:
351.56
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
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Product Name

AEA-d4, C20:4 anandamide-d4, methanol solution

方案

>99% (TLC)

表单

methanol solution

包装

pkg of 1 × 1 mL (857465W-1mg)

制造商/商品名称

Avanti Research - A Croda Brand 857465W

浓度

1 mg/mL (857465W-1mg)

脂质类型

bioactive lipids
deuterated lipids

运输

dry ice

储存温度

−20°C

SMILES字符串

O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NC([2H])([2H])C([2H])([2H])O

InChI

1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-/i20D2,21D2

InChI key

LGEQQWMQCRIYKG-KALLKTRHSA-N

一般描述

Anandamide (N-arachidonoyl ethanolamine, NArE, AEA) belongs to a large family of amidated signaling lipids, the N-acyl ethanolamines (NAEs). C20:4 AEA is a 20 carbon length side chain with four double bonds, i.e. the arachidonoyl group in AEA.

生化/生理作用

Anandamide (N-arachidonoyl ethanolamine, NArE, AEA) is a receptor for cannabinoid receptor. AEA functions as a mediator for many physiological processes including inflammation, pain, and appetite. C20:4 AEA is capable of activating vanilloid receptor (VR).

包装

2 mL Amber Glass Sealed Ampule (857465W-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

储存分类代码

3 - Flammable liquids

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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`Entourage?effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism
Smart D, et al.
British Journal of Pharmacology, 136(3), 452-458 (2002)
Gabriel M Simon et al.
The Journal of biological chemistry, 281(36), 26465-26472 (2006-07-05)
N-Acyl ethanolamines (NAEs) are a large class of signaling lipids implicated in diverse physiological processes, including nociception, cognition, anxiety, appetite, and inflammation. It has been proposed that NAEs are biosynthesized from their corresponding N-acyl phosphatidylethanolamines (NAPEs) in a single enzymatic
Gabriel M Simon et al.
The Journal of biological chemistry, 283(14), 9341-9349 (2008-01-30)
Anandamide (AEA) is an endogenous ligand of cannabinoid receptors and a well characterized mediator of many physiological processes including inflammation, pain, and appetite. The biosynthetic pathway(s) for anandamide and its N-acyl ethanolamine (NAE) congeners remain enigmatic. Previously, we proposed an

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