857501P
Avanti
16:0-17:0 cyclo PC
Avanti Research™ - A Croda Brand
别名:
1-palmitoyl-2-cis-9,10-methylenehexadecanoyl-sn-glycero-3-phosphocholine
Product Name
16:0-17:0 cyclo PC, Avanti Research™ - A Croda Brand 857501P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (857501P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 857501P
脂质类型
cardiolipins
phospholipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC1C(C1)CCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI key
MHMMFIIAMURXQM-DFCGPKRUSA-N
一般描述
16:0-17:0 cyclo PC or 1-palmitoyl-2-cis-9,10-methylenehexadecanoyl-sn-glycero-3-phosphocholine is a cyclopropane modified analog of PC. It is a glycerophospholipid and is the most important constituent of the eukaryotic cell membrane. Generally, it constitutes up to 40-50% of the cells and organelles.
生化/生理作用
Phosphatidylcholine (PC) is crucial for the synthesis of second messengers and lipid mediators. It also acts as an intermediate for the synthesis of other glycerophospholipid classes along with phosphatidylethanolamine (PE). Any disturbance in PC levels leads to various metabolic disorders.
包装
5 mL Amber Glass Screw Cap Vial (857501P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
Selma Maric et al.
Applied microbiology and biotechnology, 99(1), 241-254 (2014-10-11)
Phosphatidylcholine (PC) is a major component of eukaryotic cell membranes and one of the most commonly used phospholipids for reconstitution of membrane proteins into carrier systems such as lipid vesicles, micelles and nanodiscs. Selectively deuterated versions of this lipid have
Lian Shan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 864(1-2), 22-28 (2008-02-12)
Lysophosphatidic acid (LPA) is a class of lipids that play multiple biological functions. Several reports show that they are potential biomarkers for diagnosing ovarian cancer. Therefore, it is necessary to accurately quantify their levels in biological samples. Here we report
Nicholas C Zitomer et al.
The Journal of biological chemistry, 284(8), 4786-4795 (2008-12-20)
Fumonisin B(1) (FB(1)) is a mycotoxin that inhibits ceramide synthases (CerS) and causes kidney and liver toxicity and other disease. Inhibition of CerS by FB(1) increases sphinganine (Sa), Sa 1-phosphate, and a previously unidentified metabolite. Analysis of the latter by
Junliang Wan et al.
Journal of agricultural and food chemistry, 67(46), 12953-12961 (2019-10-23)
Most common sphingolipids are comprised of "typical" sphingoid bases (sphinganine, sphingosine, and structurally related compounds) and are produced via the condensation of l-serine with a fatty acyl-CoA by serine palmitoyltransferase. Some organisms, including mammals, also produce "atypical" sphingoid bases that
Luce Farine et al.
Scientific reports, 5, 16787-16787 (2015-11-19)
Phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are among the most abundant phospholipids in biological membranes. In many eukaryotes, the CDP-ethanolamine and CDP-choline branches of the Kennedy pathway represent major and often essential routes for the production of PE and PC, with
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