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关于此项目
经验公式（希尔记法）:
C38H75NO3
化学文摘社编号:
分子量:
594.01
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860520P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C38H75NO3/c1-3-5-7-9-11-13-15-17-18-19-20-22-24-26-28-30-32-34-38(42)39-36(35-40)37(41)33-31-29-27-25-23-21-16-14-12-10-8-6-4-2/h31,33,36-37,40-41H,3-30,32,34-35H2,1-2H3,(H,39,42)/b33-31+/t36-,37+/m0/s1
InChI key
XWBWIAOWSABHFI-NUKVNZTCSA-N
General description
C20神经酰胺(d18:1/20:0)或N-花生酰-D-赤型-鞘氨醇是一种人工合成的、由鞘氨醇和花生四烯酸组成的神经酰胺。C20神经酰胺由神经酰胺合成酶负责合成。
Application
C20神经酰胺(d18:1/20:0)已用于：
- 作为标准品，用于通过高效液相色谱/串联质谱(LC/MS2)技术定量分析肌肉组织样品中的神经酰胺含量
- 作为鞘脂代谢物定量分析的标准品
- 研究其对线粒体-胞浆应激反应(MCSR)诱发的影响
Biochem/physiol Actions
C20神经酰胺的浓度变化可作为潜在的肿瘤监测标记。
Packaging
5 mL棕色玻璃螺旋盖样品瓶（860520P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Hyun-Eui Kim et al.
Cell, 166(6), 1539-1552 (2016-09-10)
Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding diseases such as Alzheimer's, Parkinson's, and Huntington's. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work in parallel to ensure cellular
Elisabetta Albi et al.
International journal of molecular sciences, 15(7), 11555-11565 (2014-07-01)
Proliferating thyroid cells are more sensitive to UV-C radiations than quiescent cells. The effect is mediated by nuclear phosphatidylcholine and sphingomyelin metabolism. It was demonstrated that proton beams arrest cell growth and stimulate apoptosis but until now there have been
Mutay Aslan et al.
Nutrition and cancer, 1-13 (2020-04-15)
We aimed to investigate the impact of thymoquinone (TQ), on sphingolipid metabolites, ER stress and apoptotic pathways in MCF-7 and HepG2 cancer cells. Antiproliferative effect was exerted in cancer cells via TQ incubation at different doses and durations. Cell viability
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860520P-5MG | 04061835317677 |