产品名称
2-OG, Avanti Research™ - A Croda Brand 870451O
SMILES string
[H]C(CO)(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO
InChI
1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChI key
UPWGQKDVAURUGE-KTKRTIGZSA-N
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 5 mg (with screw cap/argon/foil bag (870451O-5mg))
manufacturer/tradename
Avanti Research™ - A Croda Brand 870451O
lipid type
phosphoglycerides
bioactive lipids
shipped in
dry ice
storage temp.
−20°C
General description
2-油酰基甘油（2-OG）是由胰脂肪酶（PL）催化的反应由三油酰基甘油合成的。
Application
2-油酰基甘油（2-OG）适用于脂质组学研究。
Biochem/physiol Actions
2-油酰基甘油（2-OG）在体外充当G蛋白偶联受体119（GPR119）的激动剂，并在体内刺激胰高血糖素样肽1（GLP-1）的分泌。
Packaging
5 mL PTFE小瓶，带螺旋盖/氩气/铝箔袋（870451O-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen KB, et al.
The Journal of Clinical Endocrinology and Metabolism, 96(9), E1409-E1417 (2011)
Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides
Tortoriello G, et al.
PLoS ONE, 8(7), e67865-e67865 (2013)
Ieva Vasiliauskaité-Brooks et al.
Nature, 544(7648), 120-123 (2017-03-23)
Adiponectin receptors (ADIPORs) are integral membrane proteins that control glucose and lipid metabolism by mediating, at least in part, a cellular ceramidase activity that catalyses the hydrolysis of ceramide to produce sphingosine and a free fatty acid (FFA). The crystal
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