Product Name
PAzePC, Avanti Research™ - A Croda Brand 870600P, powder
表单
powder
包装
pkg of 1 × 1 mg (870600P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 870600P
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C33H64NO10P/c1-5-6-7-8-9-10-11-12-13-14-15-18-21-24-32(37)41-28-30(29-43-45(39,40)42-27-26-34(2,3)4)44-33(38)25-22-19-16-17-20-23-31(35)36/h30H,5-29H2,1-4H3,(H-,35,36,39,40)/t30-/m1/s1
InChI key
GHQQYDSARXURNG-SSEXGKCCSA-N
一般描述
1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PAzePC) structure contains an anionic carboxyl group at the end of the short, oxidized acyl chain.
应用
1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PazePC) may be used as an oxidized lipid dopant in liposomes for examining the link between the permeation of H2O2 and the structure of lipid membranes. It may also be used as lysosomal phospholipase A2 substrate in the study of structural basis for Zn2+ mediated inhibition of lysosomal phospholipase A2.
生化/生理作用
1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PazePC) is a stable lipid oxidation product. It serves as an inter-H2O2 permeation promoter. It is the most common drug target for antipsychotic and antimicrobial agents in cells under oxidative stress at inflammatory sites.
包装
5 mL Amber Glass Screw Cap Vial (870600P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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