870608H
Avanti
4-HNE-二甲基缩醛
Avanti Research™ - A Croda Brand
别名:
(E)-4R-羟基壬烯醛-二甲基缩醛（每瓶含6.8mg，去保护后可得 ~5.2mg 4-羟基壬烯醛）
产品名称
4-HNE-二甲基缩醛, Avanti Research™ - A Croda Brand 870608H, hexane solution
方案
>99% (TLC)
表单
hexane solution
包装
pkg of 1 × 1 mL (870608H-5mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 870608H
浓度
6.8 mg/mL (870608H-5mg)
脂质类型
phosphoglycerides
bioactive lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
CCCCC[C@@H](O)/C=C/C(OC)OC
InChI key
ATGIHMSJAARJTF-AAXQSMANSA-N
一般描述
4-羟基壬烯醛（4-HNE或HNE）是细胞内脂质过氧化产生的α,β-不饱和羟基烯醛。一些研究人员假设，4-HNE在从细胞周期事件到细胞粘附的多种途径中的细胞信号转导中发挥关键作用。
二甲基缩醛衍生物是更稳定的4-HNE形式，有利于化合物在使用过程中的长期保存。在酸存在下，很容易转化为4-HNE。
二甲基缩醛衍生物是更稳定的4-HNE形式，有利于化合物在使用过程中的长期保存。在酸存在下，很容易转化为4-HNE。
包装
2mL棕色玻璃密封安瓿（870608H-5mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Aquatic Chronic 2 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Inhalation - STOT SE 3
靶器官
Central nervous system, Nervous system
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
-14.8 °F - closed cup
闪点(°C)
-26.0 °C - closed cup
法规信息
危险化学品
此项目有
Neven Zarkovic
Molecular aspects of medicine, 24(4-5), 281-291 (2003-08-02)
The review is focused on the currently major aspect of 4-hydroxynonenal (HNE) research--studies that combine biological activities of the aldehyde together with the methods of its identification in cells and tissues. Because there were some excellent reviews on HNE published
Yogesh C Awasthi et al.
Free radical biology & medicine, 37(5), 607-619 (2004-08-04)
4-Hydroxynonenal (HNE), one of the major end products of lipid peroxidation, has been shown to be involved in signal transduction and available evidence suggests that it can affect cell cycle events in a concentration-dependent manner. Glutathione S-transferases (GSTs) can modulate
N Zarković et al.
Life sciences, 65(18-19), 1901-1904 (1999-11-27)
Immunohistochemical analysis of the distribution of the lipid peroxidation product 4-hydroxynonenal (HNE) in the brain of baboons exposed to experimental hemorrhagic traumatic shock or sepsis showed that systemic oxidative stress and the thereby generated HNE affect the blood:brain barrier and
On the role of 4-hydroxynonenal in health and disease
Csala M, et al.
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1852(5), 826-838 (2015)
Rajendra Sharma et al.
European journal of biochemistry, 271(9), 1690-1701 (2004-04-21)
4-Hydroxy-2-trans-nonenal (4-HNE), one of the major end products of lipid peroxidation, has been shown to induce apoptosis in a variety of cell lines. It appears to modulate signaling processes in more than one way because it has been suggested to
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