产品名称
Trans-AzCA4, Avanti Research™ - A Croda Brand (870625P), powder
InChI
1S/C28H33N3O3/c1-3-4-6-21-9-14-24(15-10-21)30-31-25-16-11-22(12-17-25)7-5-8-28(33)29-20-23-13-18-27(34-2)26(32)19-23/h9-19,32H,3-8,20H2,1-2H3,(H,29,33)/b31-30+
InChI key
OHCVQWRUXLESDK-NVQSTNCTSA-N
SMILES string
O=C(CCCC1=CC=C(/N=N/C2=CC=C(CCCC)C=C2)C=C1)NCC3=CC(O)=C(OC)C=C3
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (870625P-5MG)
manufacturer/tradename
Avanti Research™ - A Croda Brand (870625P)
shipped in
dry ice
storage temp.
−20°C
General description
Azo-capsaicin (AzCAs) is a photo-switchable agonist of vanilloid receptor 1 (TRPV1). Azo-capsaicin 4 (AzCA4) is the most effective agonist for TRPV1. It is composed of a capsaicin head and an azobenzene ring having photoswitchable fatty acid tail. AzCA4 exists as two isomers, which are cis- and trans- AzCA4.
Packaging
5 mL Amber Glass Screw Cap Vial (870625P-5MG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Photopharmacology and opto-chemogenetics of TRPC channels-some therapeutic visions
Curcic S, et al.
Pharmacology & Therapeutics, 200, 13-26 (2019)
James Allen Frank et al.
Nature communications, 6, 7118-7118 (2015-05-23)
Fatty acids (FAs) are not only essential components of cellular energy storage and structure, but play crucial roles in signalling. Here we present a toolkit of photoswitchable FA analogues (FAAzos) that incorporate an azobenzene photoswitch along the FA chain. By
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