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Merck
CN

880170P

Avanti

C8 PEG2000 Ceramide

Avanti Research™ - A Croda Brand

别名:

N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}

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化学文摘社编号:
212116-76-2
UNSPSC Code:
12352211
NACRES:
NA.25

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产品名称

C8 PEG2000 Ceramide, Avanti Research™ - A Croda Brand 880170P, powder

InChI

1S/C119H233NO51.C2H4/c1-4-6-8-10-11-12-13-14-15-16-17-19-20-22-116(121)115(120-117(122)23-21-18-9-7-5-2)114-169-118(123)24-25-119(124)171-170-113-112-168-111-110-167-109-108-166-107-106-165-105-104-164-103-102-163-101-100-162-99-98-161-97-96-160-95-94-159

InChI key

QXQSNNJSIRCDPD-OTOABLIDSA-N

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)COC(CCC(OOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O.C=C

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (880170P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880170P

shipped in

dry ice

storage temp.

−20°C

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General description

C8 PEG2000 Ceramide, also known as N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}, is a polyethylene glycol (PEG)-modified lipid. Ceramide-PEGylated lipoplexes deliver siRNA to targeted sites more efficiently than 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE)-PEGylated lipoplexes.

Application

C8 PEG2000 Ceramide, or N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]} is suitable for PEGylated lipoplexes preparation.

Packaging

5 mL Amber Glass Screw Cap Vial (880170P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

历史批次信息供参考:

分析证书(COA)

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Anna Lechanteur et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 93, 493-503 (2016-09-07)
The delivery of small interfering RNA (siRNA) is an attractive therapeutic approach to treat several pathologies, such as viral infections or cancers. However, the stability and the efficacy of these biotherapies are still a major obstacle to their use. Cationic

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