产品名称
12:0-13:0 PI, Avanti Research™ - A Croda Brand LM1500, methanol solution
InChI key
REGULBPHXGUPTE-RBKCQXOZSA-N
SMILES string
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[NH4+]
assay
>99% (TLC)
form
methanol solution
packaging
pkg of 1 × 1 mL (LM1500-1EA)
manufacturer/tradename
Avanti Research™ - A Croda Brand LM1500
concentration
~10 μg/mL (Refer to C of A for lot specific concentration. )
application(s)
lipidomics
metabolomics
shipped in
dry ice
storage temp.
−20°C
Application
12:0-13:0 PI or 1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phospho-(1′-myo-inositol) has been used as an internal standard for lipid quantification/analysis using electrospray ionization tandem mass spectrometry (ESI-MS/MS) and liquid chromatography mass spectrometry (LC-MS).
General description
Phosphatidylinositol (PI) is commonly found in animal tissues and bacteria. PI is soluble in water and chloroform/methanol.
Packaging
2 mL Amber Glass Sealed Ampule (LM1500-1EA)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
危险化学品
此项目有
Penelope Dimas et al.
eLife, 8 (2019-05-08)
Oligodendrocytes (OLs) support neurons and signal transmission in the central nervous system (CNS) by enwrapping axons with myelin, a lipid-rich membrane structure. We addressed the significance of fatty acid (FA) synthesis in OLs by depleting FA synthase (FASN) from OL
Laura Montani et al.
The Journal of cell biology, 217(4), 1353-1368 (2018-02-13)
Myelination calls for a remarkable surge in cell metabolism to facilitate lipid and membrane production. Endogenous fatty acid (FA) synthesis represents a potentially critical process in myelinating glia. Using genetically modified mice, we show that Schwann cell (SC) intrinsic activity
Mouhannad Malek et al.
Molecular cell, 68(3), 566-580 (2017-10-24)
The PI3K signaling pathway regulates cell growth and movement and is heavily mutated in cancer. Class I PI3Ks synthesize the lipid messenger PI(3,4,5)P3. PI(3,4,5)P3 can be dephosphorylated by 3- or 5-phosphatases, the latter producing PI(3,4)P2. The PTEN tumor suppressor is thought
Alexander Fauland et al.
Journal of lipid research, 52(12), 2314-2322 (2011-10-01)
This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to
Milena Vukotic et al.
Molecular cell, 67(3), 471-483 (2017-07-18)
Mutations in mitochondrial acylglycerol kinase (AGK) cause Sengers syndrome, which is characterized by cataracts, hypertrophic cardiomyopathy, and skeletal myopathy. AGK generates phosphatidic acid and lysophosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor progression. However, the
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