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Merck
CN

S-024

Supelco

HU-210 solution

100 μg/mL in methanol, (Spice Cannabinoid), ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式(希尔记法):
C25H38O3
化学文摘社编号:
分子量:
386.57
EC 号:
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

certified reference material

质量水平

表单

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule E (Switzerland)

浓度

100 μg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology
forensics and toxicology

包装形式

single component solution

储存温度

−20°C

SMILES字符串

CCCCCCC(C)(C)c1cc(O)c2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1

InChI

1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1

InChI key

SSQJFGMEZBFMNV-WOJBJXKFSA-N

一般描述

HU-210 is a synthetic cannabinoid found in the herbal mixture “Spice.” Illicit use of this Spice cannabinoid includes smoking the herbal product to obtain a psychoactive effect. Structurally similar to (-)-Δ8-THC and 11-Hydroxy-Δ9-THC, HU-210 is considerably more potent than natural THC from cannabis and has an extended duration of action.
In July, 2009, the US Drug Enforcement Agency (DEA) placed HU-210 on its Drugs and Chemicals of Concern list. Since HU-210′s placement on this list, DEA has reported seizures of Spice herbal mixtures in Ohio and Florida. HU-210 is currently listed as a Schedule I controlled substance. In recognition of this regulatory challenge, Cerilliant supplies its certified HU-210 reference standard in a convenient, quantitative, DEA-exempt solution.

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

监管及禁止进口产品
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S E M Lewis et al.
International journal of andrology, 35(5), 731-740 (2012-03-23)
Recent societal acceptance of cannabinoids as recreational and therapeutic drugs has posed a potential hazard to male reproductive health. Mammals have a highly sophisticated endogenous cannabinoid (ECS) system that regulates male (and female) reproduction and exo-cannabinoids may influence it adversely.
C L Limebeer et al.
British journal of pharmacology, 167(5), 1126-1136 (2012-06-08)
Conditioned gaping reactions reflect nausea-induced behaviour in rats. Cannabinoid 1 receptor (CB(1) ) agonists interfere with the establishment of nausea-induced conditioned gaping; however, it is not known if their effects are mediated by an action at peripheral or central CB(1)
Lidia Martín-Couce et al.
Angewandte Chemie (International ed. in English), 51(28), 6896-6899 (2012-06-13)
Receptors made visible: The described biotin-tagged small-molecule probes with excellent affinities for the CB(1) and CB(2) cannabinoid receptors (CB(1)R and CB(2)R) enable direct visualization of these receptors in native cellular systems, including neurons, microglia, and immune cells. This method could
Vu H Nguyen et al.
Pharmacology, 89(1-2), 64-73 (2012-02-04)
Functional linkages between the cannabinoid CB(1) and the dopaminergic systems have been reported although the observations and the mechanisms hypothesizing their interactions at the G protein-coupled receptor (GPCR) functionality level are conflicting. Administration of a potent cannabinoid agonist, HU210, at
Rizi Ai et al.
Journal of molecular graphics & modelling, 38, 155-164 (2012-10-20)
Cannabinoid (CB1) receptor is a therapeutic drug target, and its structure and conformational changes after ligand binding are of great interest. To study the protein conformations in ligand bound state and assist in drug discovery, CB1 receptor homology models are

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