04-078
Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal
culture supernatant, Upstate®
别名:
Anti-AIS, Anti-AR8, Anti-DHTR, Anti-HUMARA, Anti-HYSP1, Anti-KD, Anti-NR3C4, Anti-SBMA, Anti-SMAX1, Anti-TFM
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
monoclonal
Species reactivity:
human
Application:
WB
Citations:
11
biological source
rabbit
antibody form
culture supernatant
antibody product type
primary antibodies
clone
monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer81)
Quality Level
Gene Information
human ... AR(367)
General description
99 kDa
Immunogen
A synthetic phospho-peptide surrounding Ser81 of human Androgen Receptor.
Application
Anti-phospho-Androgen Receptor (Ser81) Antibody detects level of phospho-Androgen Receptor (Ser81) & has been published & validated for use in WB.
Biochem/physiol Actions
Androgen Receptor when phosphorylated on Ser81.
Physical form
100μl of cell culture supernatant with 0.1% sodium azide
Analysis Note
Routinely evaluated by immunoblot.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Shinichiro Yamamoto et al.
Cancer science, 110(11), 3476-3485 (2019-08-28)
Octamer transcription factor 1 (OCT1) is an androgen receptor (AR)-interacting partner and regulates the expression of target genes in prostate cancer cells. However, the function of OCT1 in castration-resistant prostate cancer (CRPC) is not fully understood. In the present study
Shen Gao et al.
Journal of molecular endocrinology, 36(3), 463-483 (2006-05-25)
Androgen receptor (AR) is a ligand-activated transcription factor that mediates the action of androgens and is essential for the growth, function, and cell differentiation of the prostate gland. Here, we demonstrated that the prostate apoptosis response factor-4 (par-4) functions as
Joanne N Davis et al.
Cancer research, 66(24), 11897-11906 (2006-12-21)
Activation of E2F transcription factors, through disruption of the retinoblastoma (Rb) tumor-suppressor gene, is a key event in the development of many human cancers. Previously, we showed that homozygous deletion of Rb in a prostate tissue recombination model exhibits increased
Theodoros Karantanos et al.
Oncotarget, 7(29), 46321-46334 (2016-06-23)
Caveolin-1 (Cav-1) is overexpressed in aggressive and metastatic prostate cancer (PCa) and induces PCa cell proliferation. Androgens mediate lipid synthesis through acetyl-CoA carboxylase-1 (ACC1) and fatty acid synthase (FASN). We investigated the Cav-1-mediated lipid synthesis in the development of castration
Farideh Mehraein-Ghomi et al.
Genes & cancer, 6(9-10), 428-444 (2015-12-02)
Accumulating evidence shows that androgen receptor (AR) activation and signaling plays a key role in growth and progression in all stages of prostate cancer, even under low androgen levels or in the absence of androgen in the castration-resistant prostate cancer.
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