04-078
Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal
culture supernatant, Upstate®
别名:
Anti-AIS, Anti-AR8, Anti-DHTR, Anti-HUMARA, Anti-HYSP1, Anti-KD, Anti-NR3C4, Anti-SBMA, Anti-SMAX1, Anti-TFM
生物来源
rabbit
质量水平
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性
human
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
phosphorylation (pSer81)
基因信息
human ... AR(367)
一般描述
99 kDa
免疫原
A synthetic phospho-peptide surrounding Ser81 of human Androgen Receptor.
应用
Anti-phospho-Androgen Receptor (Ser81) Antibody detects level of phospho-Androgen Receptor (Ser81) & has been published & validated for use in WB.
生化/生理作用
Androgen Receptor when phosphorylated on Ser81.
外形
100μl of cell culture supernatant with 0.1% sodium azide
分析说明
Routinely evaluated by immunoblot.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Shinichiro Yamamoto et al.
Cancer science, 110(11), 3476-3485 (2019-08-28)
Octamer transcription factor 1 (OCT1) is an androgen receptor (AR)-interacting partner and regulates the expression of target genes in prostate cancer cells. However, the function of OCT1 in castration-resistant prostate cancer (CRPC) is not fully understood. In the present study
Shen Gao et al.
Journal of molecular endocrinology, 36(3), 463-483 (2006-05-25)
Androgen receptor (AR) is a ligand-activated transcription factor that mediates the action of androgens and is essential for the growth, function, and cell differentiation of the prostate gland. Here, we demonstrated that the prostate apoptosis response factor-4 (par-4) functions as
Joanne N Davis et al.
Cancer research, 66(24), 11897-11906 (2006-12-21)
Activation of E2F transcription factors, through disruption of the retinoblastoma (Rb) tumor-suppressor gene, is a key event in the development of many human cancers. Previously, we showed that homozygous deletion of Rb in a prostate tissue recombination model exhibits increased
Theodoros Karantanos et al.
Oncotarget, 7(29), 46321-46334 (2016-06-23)
Caveolin-1 (Cav-1) is overexpressed in aggressive and metastatic prostate cancer (PCa) and induces PCa cell proliferation. Androgens mediate lipid synthesis through acetyl-CoA carboxylase-1 (ACC1) and fatty acid synthase (FASN). We investigated the Cav-1-mediated lipid synthesis in the development of castration
Farideh Mehraein-Ghomi et al.
Genes & cancer, 6(9-10), 428-444 (2015-12-02)
Accumulating evidence shows that androgen receptor (AR) activation and signaling plays a key role in growth and progression in all stages of prostate cancer, even under low androgen levels or in the absence of androgen in the castration-resistant prostate cancer.
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