05-185
Anti-avian Src Antibody, clone EC10
clone EC10, Upstate®, from mouse
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
EC10, monoclonal
Application:
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Species reactivity:
avian
Citations:
45
Technique(s):
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-avian Src Antibody, clone EC10, clone EC10, Upstate®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
EC10, monoclonal
species reactivity
avian
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SRC(6714)
Analysis Note
routinely evaluated in (60kDa) on a RIPA lysate of chicken embryo fibroblasts (CEF)
Application
Anti-avian Src Antibody, clone EC10 detects level of avian Src & has been published & validated for use in IP, WB & IC.
Biochem/physiol Actions
specific only for avian Src; this antibody is excellent for distinguishing pp60src in cells transfected with v-src or c-src expression vectors.
General description
60 kDa
Immunogen
Recombinant chicken pp60src
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, with 0.05% sodium azide
Format: Purified
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Normal cells control the growth of neighboring transformed cells independent of gap junctional communication and SRC activity.
David B Alexander, Hitoshi Ichikawa, John F Bechberger, Virginijus Valiunas, Misao Ohki et al.
Cancer Research null
Tulsiram Prathapam et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(8), 2695-2700 (2006-02-16)
The transcription factor Myc plays a central role in the control of cellular proliferation. Myc expression is induced by growth factors in a pathway mediated by cellular Src (c-Src), but it is not clear whether Myc induction or activity is
Different responses in transformation of MDCK cells in 2D and 3D culture by v-Src as revealed by microarray techniques, RT-PCR and functional assays.
Toyli, M; Rosberg-Kulha, L; Capra, J; Vuoristo, J; Eskelinen, S
Laboratory Investigation; a Journal of Technical Methods and Pathology null
Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene.
Reynolds, A B, et al.
Molecular and cellular biology, 9, 629-638 (1989)
Jill M Dunty et al.
The Journal of biological chemistry, 277(47), 45644-45654 (2002-09-12)
The focal adhesion kinase (FAK) and cell adhesion kinase beta (CAKbeta, PYK2, CADTK, RAFTK) are highly homologous FAK family members, yet clearly have unique roles in the cell. Comparative analyses of FAK and CAKbeta have revealed intriguing differences in their
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