Merck
CN
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文件

05-533

Sigma-Aldrich

Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1

clone 22B1, Upstate®, from mouse

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别名:
Anti-Anti-CAMKA, Anti-Anti-CaMKIINalpha, Anti-Anti-CaMKIIalpha, Anti-Anti-MRD53, Anti-Anti-MRT63
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

22B1, monoclonal

种属反应性

rat

制造商/商品名称

Upstate®

技术

western blot: suitable

同位素/亚型

IgG1

UniProt登记号

运输

wet ice

靶向翻译后修饰

phosphorylation (pThr286)

基因信息

human ... CAMK2A(815)

特异性

phospho-CaM Kinase II α subunit

免疫原

Peptide corresponding to residuues 281-294 of rat Cam Kinase II alpha-subunit; recognizes phosphorylated CaM Kinase II on Threonine 286

应用

Detect phospho-CaM Kinase II using this Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1 validated for use in WB.

质量

routinely evaluated by immunoblot on rat brain microsomal protein preparation

目标描述

50kDa

外形

Format: Purified

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 1


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Su-Ying Cui et al.
Journal of neurochemistry, 136(3), 609-619 (2015-11-13)
The Ca(2+) modulation in the dorsal raphe nucleus (DRN) plays an important role in sleep-wake regulation. Calmodulin-dependent kinase II (CaMKII) is an important signal-transducing molecule that is activated by Ca(2+) . This study investigated the effects of intracellular Ca(2+) /CaMKII
B L Patton et al.
Molecular biology of the cell, 4(2), 159-172 (1993-02-01)
We have visualized the distribution of autophosphorylated type II CaM kinase in neural tissue with the use of two complementary antibodies: a monoclonal antibody that binds to the alpha and beta subunits of the kinase only when they are autophosphorylated
Overexpression of calbindin-D28K in hippocampal progenitor cells increases neuronal differentiation and neurite outgrowth.
Kim, JH; Lee, JA; Song, YM; Park, CH; Hwang, SJ; Kim, YS; Kaang, BK; Son, H
Faseb Journal null
Mar Cuadrado-Tejedor et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 42(2), 524-539 (2016-08-24)
The targeting of two independent but synergistic enzymatic activities, histone deacetylases (HDACs, class I and HDAC6) and phosphodiesterase 5 (PDE5), has recently been validated as a potentially novel therapeutic approach for Alzheimer's disease (AD). Here we report the discovery of
Comparative biology of cystic fibrosis animal models.
Fisher, JT; Zhang, Y; Engelhardt, JF
Methods in Molecular Biology null

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