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S R Bhaumik et al.
Genes & development, 15(15), 1935-1945 (2001-08-04)
Despite major advances in characterizing the eukaryotic transcriptional machinery, the function of promoter-specific transcriptional activators (activators) is still not understood. For example, in no case have the direct in vivo targets of a transcriptional activator been unambiguously identified, nor has
Qiaoran Xi et al.
The Journal of biological chemistry, 283(2), 1146-1155 (2007-11-16)
The transcription factors Smad2 and Smad3 mediate a large set of gene responses induced by the cytokine transforming growth factor beta (TGFbeta), but the extent to which their function depends on chromatin remodeling remains to be defined. We observed interactions
Geneviève Deblois et al.
Cancer research, 69(15), 6149-6157 (2009-07-23)
Estrogen-related receptor alpha (ERRalpha) is an orphan nuclear receptor, the expression of which correlates with negative prognosis in breast cancer. ERRalpha shares functional features with the estrogen receptor alpha (ERalpha) and its activity is modulated by the ERBB2 signaling pathway.
Arvind Panday et al.
Molecular biology of the cell, 28(18), 2449-2459 (2017-07-14)
The mechanistic target of rapamycin complex 1 (mTORC1) senses nutrient sufficiency and cellular stress. When mTORC1 is inhibited, protein synthesis is reduced in an intricate process that includes a concerted down-regulation of genes encoding rRNA and ribosomal proteins. The Saccharomyces
The C. elegans dosage compensation complex propagates dynamically and independently of X chromosome sequence.
Ercan, S; Dick, LL; Lieb, JD
Current Biology null
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