Merck
CN
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文件

09-143

Sigma-Aldrich

Anti-Brk Antibody

Upstate®, from rabbit

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别名:
PTK6, protein tyrosine kinase 6, breast tumor kinase, protein-tyrosine kinase BRK
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

100

抗体形式

affinity isolated antibody

antibody product type

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

同位素/亚型

IgG

NCBI登记号

NM_005975.2

UniProt登记号

Q13882

运输

wet ice

target post-translational modification

unmodified

Gene Information

human ... PTK6(5753)

特异性

Recognizes Brk (breast tumor kinase, PTK6) at approximately 52 kDa. It can also recognize the 73 kDa ELF-related protein that shares 70% homology with the immunizing peptide.

免疫原

KLH conjugated synthetic peptide corresponding to the N-terminal region of human Brk.

应用

Detect Brk using this Anti-Brk Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

质量

Routinely evaluated by immunoblot.

目标描述

52 kDa

外形

ImmunoAffinity Purified
50 µg of affinity purified rabbit polyclonal IgG in 0.02 M PBS, 250 mM sodium chloride containing 0.1% sodium azide.

储存及稳定性

Store for 1 year at 2-8°C from date of shipment.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Growth response of Escherichia coli ATCC 35218 adapted to several concentrations of sodium benzoate and potassium sorbate.
Santiesteban-Lopez NA, Rosales M, Palou E, Lopez-Malo A
Journal of Food Protection null
Andrea Haegebarth et al.
Cell cycle (Georgetown, Tex.), 4(9), 1239-1246 (2005-08-06)
The intracellular tyrosine kinase Brk is expressed in regenerating epithelial tissues with highest levels in the gastrointestinal tract and skin. In these tissues, Brk is restricted to epithelial cells that are exiting the cell cycle and undergoing terminal differentiation. While
Haoqun Qiu et al.
The Journal of biological chemistry, 277(37), 34634-34641 (2002-07-18)
Brk (breast tumor kinase) is a nonreceptor tyrosine kinase that is most closely related to the Frk family of kinases, and more distantly to Src family kinases. Brk was originally identified in a screen for tyrosine kinases that are overexpressed
Bingying Wang et al.
Current biology : CB, 32(22), 4941-4948 (2022-10-13)
Amygdalin is a cyanogenic glycoside enriched in the tissues of many edible plants, including seeds of stone fruits such as cherry (Prunus avium), peach (Prunus persica), and apple (Malus domestica). These plants biosynthesize amygdalin in defense against herbivore animals, as
Monika Kasprzycka et al.
The American journal of pathology, 168(5), 1631-1641 (2006-05-03)
Tyrosine kinases play a fundamental role in cell proliferation, survival, adhesion, and motility and have also been shown to mediate malignant cell transformation. Here we describe constitutive expression of the protein tyrosine kinase Brk in a large proportion of cutaneous
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