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Merck
CN

1.52020

Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns

L × I.D. 25 mm x 4.6 mm HPLC Column

别名:

Chromolith® HighResolution RP-18 endcapped 25-4.6 HPLC column

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UNSPSC Code:
41115709
NACRES:
SB.52
Matrix active group:
C18 bonding phase, octadecylsilane (ODS), C18 bonding phase
Pore size:
1.15 μm macroporosity, 1.5 μm macroporosity
Matrix:
highly porous
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产品名称

Chromolith® HighResolution RP-18 封端, L × I.D. 25 mm x 4.6 mm HPLC column

material

PEEK column

agency

suitable for ISO/CEN 6304.09, suitable for USP L1

product line

Chromolith®

Quality Level

packaging

1 ea of

extent of labeling

15% Carbon loading

parameter

45 °C max. temp., 50 °C max. temp.

technique(s)

LC/MS: suitable

column L × I.D.

2.5 cm × 4.6 mm

surface area

250 m2/g × 250 m2/g

matrix

highly porous

matrix active group

C18 bonding phase, octadecylsilane (ODS), C18 bonding phase

pore size

1.15 μm macroporosity, 1.5 μm macroporosity

application(s)

PFAS testing

separation technique

reversed phase

storage temp.

no temp limit

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General description

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® HighResolution RP-18 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octadecylsilane with full end-capping.

Chromolith® HighResolution RP-18 endcapped columns fall under the USP L1 Classification. The column efficiency is comparableto a 2.7 to 3 μm particle size fully porous particulate column. Chromolith® HighResolution RP-18 endcapped columns are perfectly suitable for LC-MS applications.
The column dimension of 25 mm length and 4.6 mm I.D. is the best choice for very rapid separations on any HPLC System and rapid method development.

The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes
—Connection of columns, flow gradients and the use of mobile phases with higher viscosity

The recommended Guard-columns are:
Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges (3 pieces) [1.52025] with the Chromolith® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]
The Chromolith® column coupler can be used to significantly increase the separation efficiency of Chromolith® columns by coupling several columns in series (up to 100,000 plates/per column). [1.51467]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Chromolith® HighResolution RP-18 endcapped columns are also available in 2 mm I.D. column dimension for perfect fit to UHPLC and UHPLC-MS needs.
Flyer: UHPLC-like performance - Rapid and Robust at Low Pressure - Chromolith® HighResolution RP-18 endcapped 2 mm I.D. HPLC Columns

Analysis Note

Pressure: 10 - 30 bar
Performance (anthracene)
Theoretical Plates (N/m) (Anthracene): ≥ 110000
Capacity factor (Anthracene): 3.3 - 4.6
Tailing (USP): 0.90 - 1.40 %
Selectivity
separation factor (anthracene/progesterone): 1.85 - 2.35

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

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商品

Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.

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