biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
dilution
(ELISA (1:800)
Immunoblotting (1:1000))
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
Anti-Apolipoprotein A-I, rabbit polyclonal, recognizes human apolipoprotein A-I. Does not cross-react with other apolipoproteins. It is validated for ELISA and Western blotting.
Rabbit polyclonal antibody purified by ammonium sulfate precipitation and DEAE-cellulose ion exchange chromatography. Recognizes the apolipoprotein A-I protein.
Recognizes human apolipoprotein A-I. Does not cross-react with other human apolipoproteins.
- Antibody Target Gene Symbol: APOA1
- Target Synonym: Ai, ALP-1, Apo1a, APOA-I, APOLIPOPROTEIN A-I, APOLIPOPROTEIN A-I G1, APOLIPOPROTEIN A1, Brp-14, HDLA1, LP(A-I), Ltw-1, Lvtw-1, MGC102525, MGC117399, Sep-1, Sep-2
- Entrez Gene Name: apolipoprotein A-I
- Hu Entrez ID: 335 (Related Antibodies: 178474, 178472, 178470, 178463)
- Mu Entrez ID: 11806
- Rat Entrez ID: 25081
Immunogen
Human
full length, human apolipoprotein A-I
Application
ELISA (≥1:800)
Immunoblotting (1:1000)
Immunoblotting (1:1000)
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Does not cross-react with Apolipoprotein A-II, B, C-I, C-II, C-III or E by immunoblotting. Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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wgk
WGK 1
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Elias N Glaros et al.
Journal of lipid research, 49(2), 324-331 (2007-11-06)
The serine palmitoyl transferase inhibitor myriocin potently suppresses the development of atherosclerosis in apolipoprotein E (apoE) gene knockout (apoE(-/-)) mice fed a high-fat diet. This is associated with reduced plasma sphingomyelin (SM) and glycosphingolipid levels. Furthermore, oral administration of myriocin
John T Melchior et al.
Journal of lipid research, 58(7), 1374-1385 (2017-05-10)
HDLs are a family of heterogeneous particles that vary in size, composition, and function. The structure of most HDLs is maintained by two scaffold proteins, apoA-I and apoA-II, but up to 95 other "accessory" proteins have been found associated with
Roshni R Singaraja et al.
Circulation, 114(12), 1301-1309 (2006-08-31)
Extrahepatic tissues have long been considered critical contributors of cholesterol to nascent HDL particles in the reverse cholesterol transport pathway, in which ABCA1 plays the crucial role. Recent studies, however, including both overexpression and deletion of ABCA1 selectively in the
W Sean Davidson et al.
Journal of lipid research, 57(4), 674-686 (2016-02-26)
HDL cholesterol (HDL-C) efflux function may be a more robust biomarker of coronary artery disease risk than HDL-C. To study HDL function, apoB-containing lipoproteins are precipitated from serum. Whether apoB precipitation affects HDL subspecies composition and function has not been
Sven Kinzebach et al.
BMC cell biology, 14, 48-48 (2013-10-31)
Multilineage differentiation, immunomodulation and secretion of trophic factors render mesenchymal stromal cells (MSC) highly attractive for clinical application. Human platelet derivatives such as pooled human platelet lysate (pHPL) and thrombin-activated platelet releasate in plasma (tPRP) have been introduced as alternatives
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