产品名称
星状孢子素, Staurosporine Streptomyces is a potent, cell-permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases.
Quality Level
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
General description
适合用作体外和培养细胞中的 PKC 以及其他蛋白激酶的有效抑制剂。
Application
星状孢菌素已被用作蛋白激酶抑制剂，在蛋白水平上研究了泛素蛋白连接酶E3组分N-识别蛋白5 (UBR5)介导的CDC73调控。十字孢碱已被用于诱导CHO-K1细胞系的凋亡，随后进行细胞成像和细胞裂解物提取以便进一步分析。
Biochem/physiol Actions
星状孢菌素是一种广谱蛋白激酶抑制剂，属于吲哚卡巴唑家族。它被称为典型的ATP竞争性激酶抑制剂。星状孢菌素对各种癌症都有效。它通常用于诱导不同类型细胞的凋亡。
Analysis Note
通过蛋白激酶抑制分析进行了常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 4 - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 19-123 | 04053252270697 |
| 19-123MG | 04053252332746 |